INT350584

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Context Info
Confidence 0.51
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome (Mlh1) ATPase activity (Mlh1) nucleus (Mlh1)
cell cycle (Mlh1)
Anatomy Link Frequency
lung 4
Mlh1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 36 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 126 99.38 Very High Very High Very High
Lung Cancer 18 98.66 Very High Very High Very High
Microsatellite Instability 28 92.04 High High
Chromosomal Instability 2 61.32 Quite High
Genomic Instability 14 59.28 Quite High
Toxicity 22 23.44 Low Low
Intestinal Cancer 72 22.04 Low Low
Death 8 11.68 Low Low
Stress 42 5.00 Very Low Very Low Very Low
INFLAMMATION 40 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Relative to lung tumors from nonexposed individuals, tumors from chromate workers exhibit reduced expression of MLH1 as well as signs of MLH1 hypermethylation (Takahashi et al., 2005).
Negative_regulation (reduced) of Gene_expression (expression) of MLH1 in lung associated with lung cancer and cancer
1) Confidence 0.51 Published 2011 Journal Toxicological Sciences Section Body Doc Link PMC3003834 Disease Relevance 1.10 Pain Relevance 0
Relative to lung tumors from nonexposed individuals, tumors from chromate workers exhibit reduced expression of MLH1 as well as signs of MLH1 hypermethylation (Takahashi et al., 2005).
Negative_regulation (reduced) of Gene_expression (expression) of MLH1 in lung associated with lung cancer and cancer
2) Confidence 0.37 Published 2011 Journal Toxicological Sciences Section Body Doc Link PMC3003834 Disease Relevance 1.10 Pain Relevance 0

General Comments

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