INT350708

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Context Info
Confidence 0.08
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Foxp3, Socs1) intracellular (Foxp3) embryo development (Foxp3)
DNA binding (Foxp3) cytoplasm (Foxp3)
Anatomy Link Frequency
thymus 1
Foxp3 (Mus musculus)
Socs1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 27 91.64 High High
addiction 1 54.16 Quite High
Multiple sclerosis 158 5.00 Very Low Very Low Very Low
Inflammation 28 5.00 Very Low Very Low Very Low
Central nervous system 27 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 46 88.12 High High
Repression 9 76.48 Quite High
Demyelinating Disease 175 50.20 Quite High
Disease 68 5.00 Very Low Very Low Very Low
INFLAMMATION 35 5.00 Very Low Very Low Very Low
Central Nervous System Disease 27 5.00 Very Low Very Low Very Low
Multiple Sclerosis 20 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Forkhead box P3- (Foxp3-) dependent regulation of miR155 maintains competitive fitness of Treg cell subsets by targeting SOCS1 [113]. miR-155-deficient mice have reduced numbers of Tregs, both in the thymus and periphery, due to impaired development.
Foxp3 Regulation (targeting) of SOCS1 in thymus
1) Confidence 0.08 Published 2011 Journal Autoimmune Diseases Section Body Doc Link PMC3003960 Disease Relevance 0.21 Pain Relevance 0.07

General Comments

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