INT35157

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Context Info
Confidence 0.17
First Reported 1982
Last Reported 1998
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.50
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1, GHRH) extracellular region (GH1, GHRH) cell-cell signaling (GHRH)
Anatomy Link Frequency
follicle 1
GH1 (Homo sapiens)
GHRH (Homo sapiens)
Pain Link Frequency Relevance Heat
Endogenous opioid 1 100.00 Very High Very High Very High
Clonidine 1 99.48 Very High Very High Very High
opiate 4 98.20 Very High Very High Very High
antagonist 1 97.92 Very High Very High Very High
narcan 6 97.48 Very High Very High Very High
tolerance 1 93.16 High High
Enkephalin 4 83.84 Quite High
withdrawal 1 78.08 Quite High
Parenteral administration 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypoglycemia 2 99.68 Very High Very High Very High
Congenital Anomalies 1 97.72 Very High Very High Very High
Dwarfism 3 76.48 Quite High
Syndrome 3 75.00 Quite High
Xerostomia 1 25.60 Quite Low
Microcephaly 1 25.00 Low Low
Cleidocranial Dysplasia 1 25.00 Low Low
Obesity 1 25.00 Low Low
Increased Venous Pressure Under Development 1 25.00 Low Low
Exanthema 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum GH did not respond to provocative stimuli (GHRH, L-dopa, or clonidine).
GH Neg (not) Regulation (respond) of GHRH associated with clonidine
1) Confidence 0.17 Published 1998 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 9814493 Disease Relevance 0.50 Pain Relevance 0.10
To evaluate the role of endogenous opioid peptides in prolactin (Prl), growth hormone (GH) and cortisol neuroregulation, 50 mg of the opiate antagonist naloxone was infused over 24 h to 6 normal male volunteers.
GH Regulation (role) of growth hormone associated with antagonist, narcan, endogenous opioid and opiate
2) Confidence 0.10 Published 1982 Journal Acta Endocrinol. Section Abstract Doc Link 6287782 Disease Relevance 0 Pain Relevance 0.69
The effects of BW 942C on serum growth hormone (GH), luteinizing hormone (LH), prolactin (PR), and follicle-stimulating hormone (FSH) were assessed in three of these volunteers.
GH Regulation (effects) of serum growth hormone in follicle
3) Confidence 0.02 Published 1987 Journal J Clin Pharmacol Section Abstract Doc Link 3119677 Disease Relevance 0 Pain Relevance 0.21

General Comments

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