INT351911

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Revision as of 07:32, 23 September 2012 by Daniel (Talk | contribs)

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2ry1) mitochondrion (P2ry1) plasma membrane (P2ry1)
signal transducer activity (P2ry1)
Anatomy Link Frequency
astrocytes 4
P2ry1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 12 68.88 Quite High
agonist 10 21.84 Low Low
cva 4 15.20 Low Low
imagery 30 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
primary somatosensory cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 100 95.68 Very High Very High Very High
Stress 2 88.32 High High
Brain Hemorrhage 48 79.48 Quite High
Death 10 78.80 Quite High
Necrosis 20 77.32 Quite High
Infarction 20 76.76 Quite High
Cerebral Edema 8 31.28 Quite Low
Brain Injury 8 24.32 Low Low
Hypoxia 6 21.28 Low Low
Cv Unclassified Under Development 8 20.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We recently demonstrated that stimulation of G-protein coupled purinergic receptors (P2Y1Rs) increased Ca2+ sensitive mitochondrial metabolism in astrocytes [22].
Positive_regulation (increased) of Positive_regulation (stimulation) of P2Y1Rs in astrocytes
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008710 Disease Relevance 0.77 Pain Relevance 0.03
Darby and co-workers reported that autocrine release of ATP in cultured astrocytes leads to activation of P2Y1Rs, which in turn stimulates the RVD [40].
Positive_regulation (leads) of Positive_regulation (activation) of P2Y1Rs in astrocytes
2) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008710 Disease Relevance 0.70 Pain Relevance 0

General Comments

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