INT352857

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex assembly (IKBKAP) DNA binding (IKBKAP) cytoplasm (IKBKAP)
signal transducer activity (IKBKAP) signal transduction (IKBKAP) nucleolus (IKBKAP)
TM4SF1 (Homo sapiens)
IKBKAP (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Dysautonomia 75 79.52 Quite High
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Dementia 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Spinal Muscular Atrophy 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that the PS-induced increase in TM4SF1 mRNA levels increases IKAP levels through regulation involving cell migration, which is impaired in Elongator-depleted cells [20].
Positive_regulation (increase) of TM4SF1 Positive_regulation (increases) of IKAP
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012102 Disease Relevance 0.27 Pain Relevance 0

General Comments

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