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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD80, CD28) cytosol (CD28) intracellular (CD80)
cell-cell signaling (CD80)
Anatomy Link Frequency
T cells 3
CD80 (Homo sapiens)
CD28 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 54 91.16 High High
abatacept 119 75.92 Quite High
methotrexate 25 74.68 Quite High
Potency 1 59.44 Quite High
Leflunomide 2 57.56 Quite High
Inflammation 7 31.08 Quite Low
Arthritis 4 26.40 Quite Low
corticosteroid 1 18.08 Low Low
cINOD 1 17.24 Low Low
cytokine 2 8.60 Low Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 56 91.16 High High
Disease 30 76.88 Quite High
Necrosis 2 37.80 Quite Low
Cancer 3 37.44 Quite Low
INFLAMMATION 12 31.08 Quite Low
Arthritis 3 26.40 Quite Low
Synovitis 2 24.76 Low Low
Infection 14 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Lung Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of these signals is induced by the interaction of CD80/86 on antigen-presenting cells (APCs) and CD28 on T cells.
CD80 Binding (interaction) of in T cells Positive_regulation (induced) of Gene_expression (presenting) of CD28 in T cells
1) Confidence 0.13 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012435 Disease Relevance 0.35 Pain Relevance 0.34

General Comments

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