INT353199

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.35 Pain Relevance 0

signal transduction (Plxna3) endoplasmic reticulum (Cyp4a8) intracellular (Plxna3) nucleus (Cux2) DNA binding (Cux2)

Cux2 (Rattus norvegicus) Plxna3 (Rattus norvegicus) Cyp4a8 (Rattus norvegicus)

Pain Link Frequency Relevance Heat carbamazepine 2 5.00 Bile 1 5.00 Paracetamol 1 5.00 member 8 1 5.00 antiepileptic Drug 1 5.00

Disease Link Frequency Relevance Heat Repression 3 100.00 Sprains And Strains 2 87.36 Hypertension 1 83.84 Aging 22 5.00 Toxicity 7 5.00 Stress 7 5.00 Drug-induced Liver Injury 7 5.00 Disease 4 5.00 Death 3 5.00 Injury 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These comparative life cycle expression data provide further evidence of Cux2's role in sex-specific repression of Cyp4a8.

Cux2 Regulation (role) of sex-specific Negative_regulation (repression) of Cyp4a8 associated with repression

1) Confidence 0.01 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3012673 Disease Relevance 0.35 Pain Relevance 0

General Comments

This test has worked.