INT353317

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Edn1, RHOA) cell differentiation (RHOA) mitochondrion (RHOA)
cell morphogenesis (RHOA) intracellular (RHOA) GTPase activity (RHOA)
Anatomy Link Frequency
smooth muscle 1
Edn1 (Rattus norvegicus)
RHOA (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 8 84.72 Quite High
agonist 3 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
bradykinin 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 2 84.72 Quite High
Hypersensitivity 5 70.40 Quite High
Increased Venous Pressure Under Development 9 48.32 Quite Low
Cv General 4 Under Development 6 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Hypercapnia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Spasticity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been recently demonstrated that endothelin-1, already at low concentrations, activates the RhoA – Rho-kinase pathway in the cerebrovascular smooth muscle [28].
endothelin-1 Positive_regulation (activates) of RhoA in smooth muscle
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013104 Disease Relevance 0.16 Pain Relevance 0.04

General Comments

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