INT353896

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cyp19a1) endoplasmic reticulum (Cyp19a1) cytoplasm (Cyp19a1)
Anatomy Link Frequency
spinal cord 2
Cyp19a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 9 99.68 Very High Very High Very High
spinal dorsal horn 6 85.48 High High
Glutamate 2 81.60 Quite High
Pain 6 80.44 Quite High
Dorsal horn 2 70.60 Quite High
Potency 1 66.48 Quite High
gABA 4 65.60 Quite High
opioid receptor 3 64.88 Quite High
agonist 1 63.60 Quite High
dorsal root ganglion 3 53.44 Quite High
Disease Link Frequency Relevance Heat
Nociception 18 95.28 Very High Very High Very High
Pain 6 80.44 Quite High
Ganglion Cysts 3 53.44 Quite High
Complex Regional Pain Syndromes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the specific nonsteroidal aromatase inhibitor, vorozole, was found to inhibit the phosphorylation of aromatase in the spinal cord and induce an acute inhibition of the endogenous spinal estrogen synthesis, which could consequently lead to the inhibition of nociceptive responses [6-8].
Negative_regulation (inhibit) of Phosphorylation (phosphorylation) of aromatase in spinal cord associated with nociception and spinal cord
1) Confidence 0.22 Published 2010 Journal Mol Pain Section Body Doc Link PMC3016347 Disease Relevance 0.47 Pain Relevance 0.55

General Comments

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