INT354703

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Latest revision as of 02:05, 21 September 2012

Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.11
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASIC1) transport (ASIC1) cytoskeleton (Myo18a)
plasma membrane (ASIC1) cytoplasm (Myo18a)
ASIC1 (Homo sapiens)
Myo18a (Mus musculus)
Pain Link Frequency Relevance Heat
ASIC 33 88.20 High High
Kinase C 3 33.44 Quite Low
imagery 9 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 18 84.36 Quite High
Disease 12 71.84 Quite High
Brain Injury 3 71.04 Quite High
Acidosis 12 66.64 Quite High
Death 24 61.68 Quite High
Apoptosis 3 43.76 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
Neurological Disease 3 5.00 Very Low Very Low Very Low
Demyelinating Disease 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with earlier results [38,39], a direct interaction between PICK1 and ASIC1a through the PDZ interaction is important.
ASIC1a Binding (interaction) of PDZ
1) Confidence 0.00 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0.49 Pain Relevance 0.09
Consistent with earlier studies [38,39], the PDZ domain mutant KD-AA greatly reduced its association with ASIC1a.
ASIC1a Binding (association) of PDZ
2) Confidence 0.00 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0.13 Pain Relevance 0
Consistent with earlier results [38,39], a direct interaction between PICK1 and ASIC1a through the PDZ interaction is important.
ASIC1a Binding (interaction) of PDZ
3) Confidence 0.00 Published 2010 Journal Mol Brain Section Body Doc Link PMC3018362 Disease Relevance 0.49 Pain Relevance 0.09

[edit] General Comments

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