INT356102

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Context Info
Confidence 0.32
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (App, Lrp1) plasma membrane (App, Lrp1) endosome (Lrp1)
Golgi apparatus (App) extracellular matrix organization (App) DNA binding (App)
Anatomy Link Frequency
plasma 2
App (Mus musculus)
Lrp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 50.88 Quite High
Kinase C 6 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 38 93.80 High High
Endometriosis (extended) 1 84.16 Quite High
Targeted Disruption 9 70.04 Quite High
INFLAMMATION 1 50.88 Quite High
Alzheimer's Dementia 5 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Amyloid Plaque 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An LRP-related protein 1B (LRP1B) has a similar effect, binding APP at the plasma membrane, preventing APP internalization, and leading to decreased A?
Negative_regulation (effect) of APP Binding (binding) of LRP in plasma
1) Confidence 0.32 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.71 Pain Relevance 0.03

General Comments

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