INT35963

Context Info Confidence 0.40 First Reported 1988 Last Reported 1988 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.30

DNA binding (ALB, MPG) nucleoplasm (MPG) transport (ALB) small molecule metabolic process (ALB) enzyme binding (ALB) protein complex (ALB)

ALB (Homo sapiens) MPG (Homo sapiens)

Pain Link Frequency Relevance Heat cocaine 7 83.36 local anesthetic 1 80.28

Disease Link Frequency Relevance Heat Toxicity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Two classes of binding sites were identified with affinity and capacity constants consistent with binding to alpha-1-acid glycoprotein (AAG) and albumin.

albumin Binding (binding) of AAG

1) Confidence 0.40 Published 1988 Journal Pharm. Res. Section Abstract Doc Link 3247314 Disease Relevance 0 Pain Relevance 0.30

General Comments

This test has worked.