INT38066

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Context Info
Confidence 0.41
First Reported 1987
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 14
Total Number 17
Disease Relevance 5.28
Pain Relevance 4.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MSC) DNA binding (MSC)
Anatomy Link Frequency
hepatocytes 4
smooth muscle 1
liver parenchyma 1
respiratory 1
MSC (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 12 99.84 Very High Very High Very High
Inflammation 14 99.56 Very High Very High Very High
MU agonist 4 98.92 Very High Very High Very High
chemokine 13 98.72 Very High Very High Very High
fibrosis 48 97.36 Very High Very High Very High
analgesia 3 97.24 Very High Very High Very High
Pain 10 93.84 High High
tolerance 2 92.40 High High
backache 2 92.16 High High
shoulder pain 2 90.40 High High
Disease Link Frequency Relevance Heat
Sleep Disorders 1 99.60 Very High Very High Very High
INFLAMMATION 16 99.56 Very High Very High Very High
Injury 60 99.36 Very High Very High Very High
Constipation 1 99.08 Very High Very High Very High
Vomiting 1 98.24 Very High Very High Very High
Obesity 58 97.88 Very High Very High Very High
Fibrosis 39 97.36 Very High Very High Very High
Pain 11 93.84 High High
Rupture 6 93.32 High High
Low Back Pain 2 92.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results confirm a relationship between work factors and MSC and indicate that logs could be one way to obtain a better understanding of the complex interaction of various nursing working conditions in relation to MSC.
MSC Binding (interaction) of
1) Confidence 0.41 Published 2009 Journal Appl Ergon Section Abstract Doc Link 18789431 Disease Relevance 0.64 Pain Relevance 0.48
The aims were to evaluate the inter-method reliability of a registration sheet for patient handling tasks, to study the day-to-day variation of musculoskeletal complaints (MSC) and to examine whether patient handling tasks and psychosocial factors were associated with MSC.
MSC Binding (associated) of
2) Confidence 0.41 Published 2009 Journal Appl Ergon Section Abstract Doc Link 18789431 Disease Relevance 0.62 Pain Relevance 0.48
MSC employs three aspects of standard opioid agonist treatment as incentives:
MSC Binding (employs) of associated with mu agonist
3) Confidence 0.32 Published 2002 Journal Sci Pract Perspect Section Body Doc Link PMC2851064 Disease Relevance 0.15 Pain Relevance 0.29
Some observers have interpreted the MSC model’s ultimate contingency, the 30-day medication taper, as punishment for the poorly responding patient, but this is not its intent.
MSC Binding (interpreted) of
4) Confidence 0.32 Published 2002 Journal Sci Pract Perspect Section Body Doc Link PMC2851064 Disease Relevance 0.07 Pain Relevance 0.31
Side effects associated with MSC included sedation and constipation but not nausea or respiratory difficulty.
MSC Binding (associated) of in respiratory associated with constipation, vomiting and sleep disorders
5) Confidence 0.25 Published 1987 Journal J Clin Pharmacol Section Abstract Doc Link 3680567 Disease Relevance 0.74 Pain Relevance 1.26
In vivo, both aMSC and pMSC implanted in injured and regenerating liver parenchyma were not able to differentiate into hepatocytes.
aMSC Binding (implanted) of in hepatocytes
6) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.27 Pain Relevance 0.07
In our study using immunodeficient recipients, we observed long-term engraftment of MSC in liver parenchyma.
MSC Binding (engraftment) of in liver parenchyma
7) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.22 Pain Relevance 0.04
Engrafted MSC in liver express alpha smooth muscle actin and their localization merges with collagen deposition
MSC Binding (merges) of in smooth muscle
8) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.10 Pain Relevance 0.05
We analyzed telomerase activity of aMSC and pMSC in order to determine whether differences in expansion capacities could be related to different activity of telomerase (Fig. 2).
pMSC Spec (analyzed) Binding (activity) of
9) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.08 Pain Relevance 0
In vivo, both aMSC and pMSC implanted in injured and regenerating liver parenchyma were not able to differentiate into hepatocytes.
aMSC Binding (regenerating) of in hepatocytes
10) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.27 Pain Relevance 0.07
In vivo, both aMSC and pMSC implanted in injured and regenerating liver parenchyma were not able to differentiate into hepatocytes.
pMSC Binding (implanted) of in hepatocytes
11) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.27 Pain Relevance 0.07
Incubation of MSC with Huh-7 cells-conditioned medium containing 5% FCS showed that factors secreted by Huh-7 cells induce ?
MSC Binding (Incubation) of
12) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0 Pain Relevance 0
Several studies indicate that MSC might have the ability to cross cell lineage boundaries and differentiate towards or into hepatocytes in vitro.
MSC Spec (might) Binding (cross) of in hepatocytes
13) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.22 Pain Relevance 0
We analyzed telomerase activity of aMSC and pMSC in order to determine whether differences in expansion capacities could be related to different activity of telomerase (Fig. 2).
aMSC Spec (analyzed) Binding (activity) of
14) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.08 Pain Relevance 0
In support of this, it is now widely accepted that MSC are associated with microvasculature and are probably pericytic in nature [45].
MSC Binding (associated) of
15) Confidence 0.09 Published 2008 Journal J Orthop Surg Section Body Doc Link PMC2515295 Disease Relevance 0.17 Pain Relevance 0.14
AL designed the study and performed the data analysis and interpretation as part of the MSc in Palliative Care at King's College London.
MSc Binding (part) of associated with palliative
16) Confidence 0.08 Published 2005 Journal BMC Palliat Care Section Body Doc Link PMC1277827 Disease Relevance 0.52 Pain Relevance 0.24
The increase in inflammatory chemokine concentration at the site of inflammation is a key mediator of trafficking of MSC to the site of injury.
MSC Binding (trafficking) of associated with chemokine, inflammation and injury
17) Confidence 0.03 Published 2010 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2962904 Disease Relevance 0.86 Pain Relevance 0.62

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