INT39201

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Context Info
Confidence 0.03
First Reported 1985
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gh1) signal transduction (Gh1) mitochondrion (Gh1)
extracellular space (Gh1) extracellular region (Gh1) plasma membrane (Gh1)
Olr824 (Rattus norvegicus)
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 100.00 Very High Very High Very High
gABA 6 99.36 Very High Very High Very High
antagonist 2 99.16 Very High Very High Very High
Opioid 2 95.36 Very High Very High Very High
GABAergic 2 94.56 High High
Intracerebroventricular 2 85.60 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering our previous findings that rat GH release induced by FK33-824 was blunted by GABA antagonists (Endocrinology 103:1033, 1981), these results suggest that GH secretion induced by opioid peptides via GABAergic mechanisms is mediated, at least in part, by hypothalamic GRF in the rat.
FK33-824 Positive_regulation (induced) of Localization (release) of GH associated with gaba, gabaergic, antagonist and opioid
1) Confidence 0.03 Published 1985 Journal Endocrinology Section Abstract Doc Link 3926462 Disease Relevance 0 Pain Relevance 0.46
Rabbit anti-rat GRF serum also blunted GH release induced by a Met5-enkephalin analog, FK33-824 (10 micrograms/100 g BW, iv) in conscious rats.
FK33-824 Positive_regulation (induced) of Localization (release) of GH associated with enkephalin
2) Confidence 0.03 Published 1985 Journal Endocrinology Section Abstract Doc Link 3926462 Disease Relevance 0 Pain Relevance 0.44

General Comments

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