INT40021

Context Info Confidence 0.59 First Reported 1985 Last Reported 2010 Negated 1 Speculated 0 Reported most in Title Documents 4 Total Number 4 Disease Relevance 1.53 Pain Relevance 0.53

extracellular space (Agt) aging (Agt) extracellular region (Agt) extracellular matrix organization (Agt)

Anatomy Link Frequency nucleus 2 Agt (Rattus norvegicus)

Pain Link Frequency Relevance Heat antinociception 5 95.52 antagonist 4 91.04 medulla 1 87.36 tail-flick 3 72.92 anesthesia 4 71.08 imagery 2 48.40 Hippocampus 1 16.40 fibrosis 4 5.00 ketamine 3 5.00 Catecholamine 3 5.00

Disease Link Frequency Relevance Heat Hypertension 43 95.04 Hypoxia 54 93.52 Heart Rate Under Development 11 87.84 Coronary Heart Disease 5 80.44 Pressure Volume 2 Under Development 1 75.12 Left Ventricular Hypertrophy 16 74.28 Targeted Disruption 2 67.36 Increased Venous Pressure Under Development 1 66.08 Stress 1 61.44 Hypertrophy 5 23.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Also, the FITC-labeled Ang IV binding was not affected by the addition of excessive amount of Sarile (Fig. 1C,F,I), which saturated the AT1 and AT2 binding sites.

Neg (not) Regulation (affected) of Ang IV Binding (binding) of

1) Confidence 0.59 Published 2007 Journal The open cardiovascular medicine journal Section Body Doc Link PMC2570565 Disease Relevance 0.37 Pain Relevance 0

Previous studies have shown that Ang 1–7 partially prevented the pressoric response elicited by Ang II in SAD rats but not in sham?

Regulation (response) of Ang II Binding (elicited) of

2) Confidence 0.43 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC3020347 Disease Relevance 0.85 Pain Relevance 0.05

[Effects of sex steroid hormones on vascular reactivity to angiotensin II in castrated rat].

Regulation ([Effects) of angiotensin II Binding (reactivity) of

3) Confidence 0.41 Published 1985 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Title Doc Link 4086908 Disease Relevance 0.17 Pain Relevance 0.07

Participation of AT1 and AT2 receptors in the differential interaction between angiotensin II or III and alpha-2 adrenoceptors in the nucleus reticularis gigantocellularis in cardiovascular regulation and antinociception in rats.

Regulation (Participation) of angiotensin II Binding (interaction) of in nucleus associated with antinociception

4) Confidence 0.30 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 8930186 Disease Relevance 0.15 Pain Relevance 0.42

General Comments

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