INT4028

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Context Info
Confidence 0.54
First Reported 1976
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 1.55
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (HYAL1) hydrolase activity, acting on glycosyl bonds (HYAL1) cell death (HYAL1)
extracellular region (HYAL1) carbohydrate metabolic process (HYAL1) lysosome (HYAL1)
Anatomy Link Frequency
plasma 6
HYAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Acupuncture 7 100.00 Very High Very High Very High
analgesia 2 100.00 Very High Very High Very High
Pain 14 99.52 Very High Very High Very High
Enkephalin 1 98.12 Very High Very High Very High
Opioid 6 97.48 Very High Very High Very High
noradrenaline 3 93.84 High High
antagonist 21 89.92 High High
narcan 5 89.04 High High
Osteoarthritis 45 88.64 High High
Analgesic 3 76.80 Quite High
Disease Link Frequency Relevance Heat
Pain 13 99.52 Very High Very High Very High
Decompression Sickness 2 98.04 Very High Very High Very High
Prostate Cancer 2 98.00 Very High Very High Very High
Metastasis 1 91.92 High High
Endometriosis (extended) 1 90.08 High High
Disease 5 89.68 High High
Osteoarthritis 46 88.64 High High
Galactorrhea 124 83.72 Quite High
Rheumatoid Arthritis 2 76.64 Quite High
Hirsutism 1 49.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fourteen antirheumatoid drugs were tested for their effects on the in vitro hyaluronidase activity of normal human serum.
Regulation (effects) of hyaluronidase
1) Confidence 0.54 Published 1976 Journal Clin. Biochem. Section Abstract Doc Link 954180 Disease Relevance 0.08 Pain Relevance 0.07
There were no changes in menstrual pattern or plasma hormone levels and no breakthrough vaginal bleeding in patients treated with Afimoxifene.
Neg (no) Regulation (changes) of plasma hormone in plasma
2) Confidence 0.39 Published 2007 Journal Breast Cancer Res. Treat. Section Body Doc Link 17351746 Disease Relevance 0 Pain Relevance 0
First, we tested the effects of both fruit powders on the activities of the enzymes hyaluronidase and collagenase type 2.
Regulation (effects) of hyaluronidase
3) Confidence 0.05 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Abstract Doc Link PMC2529383 Disease Relevance 0.25 Pain Relevance 0.13
Little is known, however, about dose-dependency of estrogen effects on plasma hormone levels.
Regulation (effects) of plasma hormone in plasma
4) Confidence 0.00 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2376090 Disease Relevance 0.31 Pain Relevance 0
Effect of high-dose medroxyprogesterone acetate on plasma hormone levels and pain relief in patients with advanced prostatic cancer.
Regulation (Effect) of plasma hormone in plasma associated with pain and prostate cancer
5) Confidence 0.00 Published 1990 Journal Br J Urol Section Title Doc Link 1692498 Disease Relevance 0.74 Pain Relevance 0.50
Changes in plasma hormone levels were studied in anesthetized dogs during decompression sickness.
Regulation (Changes) of plasma hormone in plasma associated with decompression sickness
6) Confidence 0.00 Published 1987 Journal Undersea Biomed Res Section Abstract Doc Link 2820102 Disease Relevance 0.17 Pain Relevance 0
Systemic administration of opioid peptides, methionine-enkephalin and beta-endorphin, chronically, lowered gonadotropin levels in plasma and had an inhibitory effect mainly on the testicular enzymes hyaluronidase, acid phosphatase and on incorporation of 3[H] thymidine in the tissue.
Regulation (effect) of testicular enzymes hyaluronidase in plasma associated with enkephalin and opioid
7) Confidence 0.00 Published 1998 Journal Indian J. Exp. Biol. Section Abstract Doc Link 9717445 Disease Relevance 0 Pain Relevance 0.61
Effects of acupuncture and transcutaneous stimulation analgesia on plasma hormone levels during and after major abdominal surgery.
Regulation (Effects) of plasma hormone in plasma associated with acupuncture and analgesia
8) Confidence 0.00 Published 1993 Journal Eur J Anaesthesiol Section Title Doc Link 8388332 Disease Relevance 0 Pain Relevance 0.50

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