INT40845

Context Info Confidence 0.16 First Reported 1982 Last Reported 1982 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.16

extracellular space (Ca2, Pla2g1b) cytosol (Ca2) extracellular region (Pla2g1b) lyase activity (Ca2) response to stress (Ca2) cytoplasm (Ca2)

Ca2 (Rattus norvegicus) Pla2g1b (Rattus norvegicus)

Pain Link Frequency Relevance Heat Glutamate 1 87.52 tetrodotoxin 1 79.44 Neurotransmitter 1 65.92

Disease Link Frequency Relevance Heat Toxicity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Binding occurs in the absence of divalent cations, but the rate of synaptic blockade is increased by Ca2+, which activates the intrinsic phospholipase A2 activity of the toxin.

Ca2 Positive_regulation (activates) of phospholipase A2

1) Confidence 0.16 Published 1982 Journal J. Neurochem. Section Abstract Doc Link 6123559 Disease Relevance 0 Pain Relevance 0.16

General Comments

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