INT41610

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Context Info
Confidence 0.42
First Reported 1981
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.50
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 1
IGHD@ (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 1 90.92 High High
Pain 1 84.08 Quite High
Inflammation 2 68.36 Quite High
Spinal cord 2 67.76 Quite High
Arthritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 63 98.58 Very High Very High Very High
Spontaneous Fractures 3 93.84 High High
Alzheimer's Dementia 4 90.56 High High
Paraproteinemias 1 85.96 High High
Pain 1 84.08 Quite High
Spinal Cord Diseases 1 80.72 Quite High
Amyloidosis 3 77.32 Quite High
Bacterial Infection 17 72.56 Quite High
Retrograde Degeneration 1 71.76 Quite High
INFLAMMATION 2 68.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lambda light chains were the sole contributors to a selective increase in IgD, with a concomitant reduction of IgA, IgG, and IgM.
Positive_regulation (increase) of IgD
1) Confidence 0.42 Published 1981 Journal J. Neurol. Section Abstract Doc Link 6169807 Disease Relevance 0.98 Pain Relevance 0.15
In SLE patients, we found disturbances of peripheral B-cell homeostasis with accumulation of IgD+ CD38++ transitional B cells and CD27++ PCs.
Positive_regulation (accumulation) of IgD in B cells associated with systemic lupus erythematosus
2) Confidence 0.06 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.51 Pain Relevance 0.08

General Comments

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