INT4218

Context Info Confidence 0.63 First Reported 1976 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 7 Total Number 7 Disease Relevance 2.76 Pain Relevance 0.31

extracellular region (IGHG3)

Anatomy Link Frequency brain 1 sperms 1 IGHG3 (Homo sapiens)

Pain Link Frequency Relevance Heat Enkephalin 1 90.16 chemokine 3 90.00 Bile 1 88.92 Cholecystokinin 1 88.40 abdominal pain 1 85.00 headache 3 24.24 Pain 4 23.80 Inflammation 7 5.00 cytokine 5 5.00 antagonist 3 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 48 99.82 Hyperplasia 3 95.88 Hepatitis B Virus Infection 23 88.72 Infection 205 87.92 Irritable Bowel Syndrome / Irritable Bowel Syndrome Super 1 87.52 Sprains And Strains 9 85.56 Diarrhoea 1 85.52 Abdominal Pain 1 85.00 Skin Cancer 1 78.84 Agammaglobulinemia 1 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

IgM reactivities to brain proteins were measured using the same extract as described for IgG (data not shown).

Transcription (described) of IgG in brain

1) Confidence 0.63 Published 2005 Journal Malar J Section Body Doc Link PMC548665 Disease Relevance 0.36 Pain Relevance 0

In addition, transcripts of IgM, IgD, IgG1, IgG3, IgE, IgA, and the T cell receptor a gene were detected in single sperms.

Transcription (transcripts) of IgG3 in sperms

2) Confidence 0.61 Published 1998 Journal Mol. Gen. Genet. Section Abstract Doc Link 9645429 Disease Relevance 0.08 Pain Relevance 0.18

Levels of IgG2 and IgG4 were undetectable in most people and when detected, were very low.

Transcription (Levels) of IgG4

3) Confidence 0.43 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1523344 Disease Relevance 0.55 Pain Relevance 0

The serum immunoelectrophoretic pattern showed a virtual absence of IgA and IgM and a very decreased level of IgG.

Transcription (level) of IgG

4) Confidence 0.18 Published 1976 Journal Endoscopy Section Abstract Doc Link 1026394 Disease Relevance 0.42 Pain Relevance 0.09

The ELISA protocol detected IgG and IgM antibodies directed against CHIKV antigens.

Transcription (detected) of IgG

5) Confidence 0.09 Published 2010 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2927496 Disease Relevance 0 Pain Relevance 0

For IgM testing, IgG was absorbed before testing by Biosorb resin (Biomed, Munich, Germany).

Transcription (absorbed) of IgG

6) Confidence 0.04 Published 2008 Journal Emerging Infectious Diseases Section Body Doc Link PMC2570846 Disease Relevance 0.31 Pain Relevance 0

Anti-HIV IgA and IgG antibodies were detected in CVF obtained from heterosexual ESN women [103-113].

Transcription (detected) of IgG associated with acquired immune deficiency syndrome or hiv infection

7) Confidence 0.01 Published 2010 Journal Proteome Sci Section Body Doc Link PMC3016264 Disease Relevance 0.95 Pain Relevance 0.04

General Comments

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