INT44013

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Context Info
Confidence 0.36
First Reported 1983
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd86)
Anatomy Link Frequency
B cells 2
Cd86 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 6 97.00 Very High Very High Very High
Demyelination 1 93.04 High High
Sciatic nerve 2 91.80 High High
Inflammation 1 89.08 High High
spinal inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 6 97.00 Very High Very High Very High
Demyelinating Disease 1 93.04 High High
Disease 2 89.84 High High
INFLAMMATION 1 89.08 High High
Immunization 1 84.52 Quite High
Syndrome 1 63.84 Quite High
Autoimmune Disease 1 58.72 Quite High
Disease Susceptibility 1 28.00 Quite Low
Low Back Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cross-reactivity with B7 is attributed to a B27-like epitope on the B7 antigen but which, as determined by cytotoxicity blocking studies, is distinct from the B7 allospecific epitope itself.
Positive_regulation (attributed) of B7 Binding (Cross-reactivity) of
1) Confidence 0.36 Published 1983 Journal Br. J. Rheumatol. Section Abstract Doc Link 6360285 Disease Relevance 0.09 Pain Relevance 0
Evidently, CD28 is required for interaction with B7 to regulate the activation of T and B cells that initiates development of EAN.
Positive_regulation (required) of B7 Binding (interaction) of in B cells associated with neuritis
2) Confidence 0.26 Published 2001 Journal J. Neuroimmunol. Section Abstract Doc Link 11240022 Disease Relevance 0.92 Pain Relevance 0.63

General Comments

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