INT46885

Context Info Confidence 0.43 First Reported 1982 Last Reported 1982 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.23 Pain Relevance 0.43

mitochondrion (Maoa) oxidoreductase activity (Maoa)

Anatomy Link Frequency brain 2 Maoa (Mus musculus)

Pain Link Frequency Relevance Heat Clonidine 3 99.52 gABA 2 94.36 monoamine 2 81.08

Disease Link Frequency Relevance Heat Death 1 76.76 Convulsion 2 76.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Clonidine, unlike diazepam, also inhibited the increase in brain MAO activity.

Negative_regulation (inhibited) of Positive_regulation (increase) of MAO in brain associated with clonidine

1) Confidence 0.43 Published 1982 Journal J. Vet. Pharmacol. Ther. Section Abstract Doc Link 7143555 Disease Relevance 0.23 Pain Relevance 0.43

General Comments

This test has worked.