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Context Info
Confidence 0.13
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.09
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Klk1c8)
Anatomy Link Frequency
mast cell 1
Klk1c8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 9 93.08 High High
metalloproteinase 20 87.20 High High
chemokine 1 87.12 High High
Inflammation 65 76.16 Quite High
tolerance 1 64.24 Quite High
fibrosis 9 54.04 Quite High
Inflammatory marker 1 52.44 Quite High
substance P 4 50.00 Quite Low
Chronic pancreatitis 2 47.04 Quite Low
agonist 1 40.08 Quite Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 105 99.56 Very High Very High Very High
Myocardial Infarction 6 98.00 Very High Very High Very High
Wound Healing 6 93.60 High High
Increased Venous Pressure Under Development 4 93.56 High High
Osteoporosis 6 86.72 High High
Death 2 85.40 High High
Hypersensitivity 1 77.76 Quite High
Stress 36 77.00 Quite High
INFLAMMATION 79 76.16 Quite High
Pharyngitis 1 74.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP, aprotinin (serine protease inhibitor), and ketotifen (mast cell stabilizer) were infused into the splenic artery of rats.
Negative_regulation (inhibitor) of serine protease in mast cell
1) Confidence 0.13 Published 1994 Journal Gastroenterology Section Body Doc Link 7507874 Disease Relevance 0.09 Pain Relevance 0
Therefore, it is well known that the inhibition of the serine protease DPP-IV in type 2 diabetes treatment prevents its activation of insulin-releasing peptide hormones.
Negative_regulation (inhibition) of serine protease associated with diabetes mellitus
2) Confidence 0.10 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2905949 Disease Relevance 0.79 Pain Relevance 0.21
Inhibition of the serine protease plasmin appears to have therapeutic advantage in myocardial infarct patients.

Negative_regulation (Inhibition) of serine protease associated with myocardial infarction
3) Confidence 0.02 Published 2008 Journal The Open Dentistry Journal Section Body Doc Link PMC2581528 Disease Relevance 1.21 Pain Relevance 0.08

General Comments

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