INT48380

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Context Info
Confidence 0.41
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CSF3) extracellular region (CSF3) cell adhesion (SELL)
plasma membrane (SELL) enzyme binding (CSF3)
Anatomy Link Frequency
neutrophils 4
CSF3 (Homo sapiens)
SELL (Homo sapiens)
Pain Link Frequency Relevance Heat
local anesthetic 4 85.36 High High
lidocaine 10 84.00 Quite High
Inflammation 4 34.00 Quite Low
cytokine 2 28.80 Quite Low
Disease Link Frequency Relevance Heat
Adhesions 6 100.00 Very High Very High Very High
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) enhanced superoxide (O2-) release in human neutrophils stimulated by the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and inversely regulated the surface expression of cellular adhesion molecules, leukocyte adhesion molecule-1 (LAM-1) and CD11b/CD18 leukocyte integrin, on human neutrophils; that is, rhG-CSF downregulated the expression of LAM-1 and upregulated the expression of CD11b on neutrophils.
granulocyte colony-stimulating factor Regulation (regulated) of Gene_expression (expression) of LAM-1 in neutrophils associated with adhesions
1) Confidence 0.41 Published 1994 Journal Exp. Hematol. Section Abstract Doc Link 7513653 Disease Relevance 0.20 Pain Relevance 0.44
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) enhanced superoxide (O2-) release in human neutrophils stimulated by the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and inversely regulated the surface expression of cellular adhesion molecules, leukocyte adhesion molecule-1 (LAM-1) and CD11b/CD18 leukocyte integrin, on human neutrophils; that is, rhG-CSF downregulated the expression of LAM-1 and upregulated the expression of CD11b on neutrophils.
granulocyte colony-stimulating factor Regulation (regulated) of Gene_expression (expression) of leukocyte adhesion molecule-1 in neutrophils associated with adhesions
2) Confidence 0.41 Published 1994 Journal Exp. Hematol. Section Abstract Doc Link 7513653 Disease Relevance 0.20 Pain Relevance 0.39

General Comments

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