INT48921

From wiki-pain
(Difference between revisions)
Jump to: navigation, search
(Generated page)
 
(Generated page)
 
Line 10: Line 10:
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1995
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:1995|1995]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 47: Line 47:
 
style=filled,
 
style=filled,
 
fillcolor=yellow,
 
fillcolor=yellow,
URL=Regulation
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Regulation"
 
];
 
];
 
node2
 
node2
Line 55: Line 55:
 
fontcolor=white,
 
fontcolor=white,
 
label="Mapk1",
 
label="Mapk1",
URL="Mapk1"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:116590"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 69: Line 69:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[nucleoplasm]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:nucleoplasm|nucleoplasm]] ([[G:116590|Mapk1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[mitochondrion]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:mitochondrion|mitochondrion]] ([[G:116590|Mapk1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[Golgi apparatus]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:Golgi apparatus|Golgi apparatus]] ([[G:116590|Mapk1]])
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[protein complex]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:protein complex|protein complex]] ([[G:116590|Mapk1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[microtubule organizing center]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:microtubule organizing center|microtubule organizing center]] ([[G:116590|Mapk1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[cytoplasm]] ([[Mapk1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:cytoplasm|cytoplasm]] ([[G:116590|Mapk1]])
 
|-
 
|-
 
|}
 
|}
Line 83: Line 83:
 
{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:628|thoracic aorta]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:thoracic aorta|thoracic aorta]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|4
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:581|hippocampus]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:hippocampus|hippocampus]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|3
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:452|medulla]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:medulla|medulla]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:364|spinal cord]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:spinal cord|spinal cord]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:732|kidney cortex]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:kidney cortex|kidney cortex]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
Line 114: Line 114:
 
{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[medulla]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:medulla|medulla]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 235
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 235
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dopamine]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Dopamine|Dopamine]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 113
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 113
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.98
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.98
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hippocampus]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Hippocampus|Hippocampus]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 190
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 190
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Spinal cord]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Spinal cord|Spinal cord]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 256
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 256
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dorsal horn]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Dorsal horn|Dorsal horn]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 435
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 435
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.06
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.06
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Lasting pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Lasting pain|Lasting pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 122
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 122
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Rostral ventrolateral medulla]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Rostral ventrolateral medulla|Rostral ventrolateral medulla]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 110
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 110
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[painful pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:painful pain|painful pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[allodynia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:allodynia|allodynia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.24
Line 175: Line 175:
 
{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Diabetes Mellitus]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Diabetes Mellitus|Diabetes Mellitus]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1422
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1422
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.92
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Urological Neuroanatomy]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Urological Neuroanatomy|Urological Neuroanatomy]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 13
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 13
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 587
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 587
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.06
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.06
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stress]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Stress|Stress]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.66
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Death]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Death|Death]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 125
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 125
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apoptosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Apoptosis|Apoptosis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neuropathic Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Neuropathic Pain|Neuropathic Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 61
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 61
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Nervous System Injury]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Nervous System Injury|Nervous System Injury]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 95.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 95.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Frailty]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Frailty|Frailty]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 94.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 94.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pheochromocytoma]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pheochromocytoma|Pheochromocytoma]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.16
Line 254: Line 254:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (not) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affected</span>) of <span style="color:#800000">'''ERK1/2'''</span> in <span style="color:#808000">medulla</span> associated with <span style="color:#FF0000">'''medulla'''</span> and <span style="color:#FF0000">'''rostral ventrolateral medulla'''</span>
+
|  Neg (not) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affected</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]] in [[A:medulla|<span style="color:#808000">medulla</span>]] associated with <span style="color:#FF0000">'''medulla'''</span> and <span style="color:#FF0000">'''rostral ventrolateral medulla'''</span>
 
|-
 
|-
 
|}
 
|}
Line 265: Line 265:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Biomed Sci|J Biomed Sci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Biomed Sci|J Biomed Sci]]
Line 285: Line 285:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">changes</span>) of <span style="color:#800000">'''ERK2'''</span> in <span style="color:#808000">spinal cord dorsal horn</span> associated with <span style="color:#FF0000">'''pain'''</span>, <span style="color:#FF0000">'''lasting pain'''</span>, <span style="color:#FF0000">'''dorsal horn'''</span>, <span style="color:#FF0000">'''painful pain'''</span>, <span style="color:#FF0000">'''hippocampus'''</span> and <span style="color:#FF0000">'''spinal cord'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">changes</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]] in [[A:spinal cord dorsal horn|<span style="color:#808000">spinal cord dorsal horn</span>]] associated with <span style="color:#FF0000">'''pain'''</span>, <span style="color:#FF0000">'''lasting pain'''</span>, <span style="color:#FF0000">'''dorsal horn'''</span>, <span style="color:#FF0000">'''painful pain'''</span>, <span style="color:#FF0000">'''hippocampus'''</span> and <span style="color:#FF0000">'''spinal cord'''</span>
 
|-
 
|-
 
|}
 
|}
Line 296: Line 296:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.43
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.43
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 316: Line 316:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulated</span>) of <span style="color:#800000">'''extracellular signal-regulated kinase 1 and 2'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulated</span>) of [[G:116590|<span style="color:#800000">'''extracellular signal-regulated kinase 1 and 2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 327: Line 327:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.38
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.38
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2006
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2006|2006]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Exp. Neurol.|Exp. Neurol.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Exp. Neurol.|Exp. Neurol.]]
Line 347: Line 347:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (not) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affect</span>) of <span style="color:#800000">'''extracellular signal-regulated protein kinase 1 and 2'''</span>
+
|  Neg (not) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affect</span>) of [[G:116590|<span style="color:#800000">'''extracellular signal-regulated protein kinase 1 and 2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 358: Line 358:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.34
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.34
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2003
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2003|2003]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Neuroscience|Neuroscience]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Neuroscience|Neuroscience]]
Line 378: Line 378:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Spec (examined) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">involvement</span>) of <span style="color:#800000">'''p38 MAPK'''</span> in <span style="color:#808000">spinal</span>
+
|  Spec (examined) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">involvement</span>) of [[G:116590|<span style="color:#800000">'''p38 MAPK'''</span>]] in [[A:spinal|<span style="color:#808000">spinal</span>]]
 
|-
 
|-
 
|}
 
|}
Line 389: Line 389:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.31
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.31
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biol. Pharm. Bull.|Biol. Pharm. Bull.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biol. Pharm. Bull.|Biol. Pharm. Bull.]]
Line 409: Line 409:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affects</span>) of <span style="color:#800000">'''ERK2'''</span> in <span style="color:#808000">hippocampus</span> associated with <span style="color:#FF0000">'''dopamine'''</span> and <span style="color:#FF0000">'''hippocampus'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affects</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]] in [[A:hippocampus|<span style="color:#808000">hippocampus</span>]] associated with <span style="color:#FF0000">'''dopamine'''</span> and <span style="color:#FF0000">'''hippocampus'''</span>
 
|-
 
|-
 
|}
 
|}
Line 420: Line 420:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.27
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.27
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2006
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2006|2006]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 440: Line 440:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (not) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affected</span>) of <span style="color:#800000">'''ERK1/2'''</span> in <span style="color:#808000">upper</span>
+
|  Neg (not) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affected</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]] in [[A:upper|<span style="color:#808000">upper</span>]]
 
|-
 
|-
 
|}
 
|}
Line 451: Line 451:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2001
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2001|2001]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Cell Biol|BMC Cell Biol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Cell Biol|BMC Cell Biol]]
Line 471: Line 471:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">immunoreactivity</span>) of <span style="color:#800000">'''ERK2'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">immunoreactivity</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 482: Line 482:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 503: Line 503:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Spec (might) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">responses</span>) of <span style="color:#800000">'''pERK2'''</span> in <span style="color:#808000">hippocampus</span> associated with <span style="color:#FF0000">'''nociception'''</span>, <span style="color:#FF0000">'''pain'''</span>, <span style="color:#FF0000">'''hippocampus'''</span> and <span style="color:#FF0000">'''spinal cord'''</span>
+
|  Spec (might) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">responses</span>) of [[G:116590|<span style="color:#800000">'''pERK2'''</span>]] in [[A:hippocampus|<span style="color:#808000">hippocampus</span>]] associated with <span style="color:#FF0000">'''nociception'''</span>, <span style="color:#FF0000">'''pain'''</span>, <span style="color:#FF0000">'''hippocampus'''</span> and <span style="color:#FF0000">'''spinal cord'''</span>
 
|-
 
|-
 
|}
 
|}
Line 514: Line 514:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 534: Line 534:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">sensitive</span>) of <span style="color:#800000">'''ERK2'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">sensitive</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 545: Line 545:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 566: Line 566:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (no) Spec (examined) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">changes</span>) of <span style="color:#800000">'''ERK2'''</span> in <span style="color:#808000">hippocampus</span> associated with <span style="color:#FF0000">'''hippocampus'''</span>
+
|  Neg (no) Spec (examined) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">changes</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]] in [[A:hippocampus|<span style="color:#808000">hippocampus</span>]] associated with <span style="color:#FF0000">'''hippocampus'''</span>
 
|-
 
|-
 
|}
 
|}
Line 577: Line 577:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 597: Line 597:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">concentrations</span>) of <span style="color:#800000">'''ERK2'''</span> in <span style="color:#808000">brain</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">concentrations</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]] in [[A:brain|<span style="color:#808000">brain</span>]]
 
|-
 
|-
 
|}
 
|}
Line 608: Line 608:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.25
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1995
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:1995|1995]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J. Neurosci.|J. Neurosci.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J. Neurosci.|J. Neurosci.]]
Line 629: Line 629:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (no) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">alterations</span>) of <span style="color:#800000">'''tERK2'''</span> in <span style="color:#808000">spinal cord</span> associated with <span style="color:#FF0000">'''spinal cord'''</span>
+
|  Neg (no) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">alterations</span>) of [[G:116590|<span style="color:#800000">'''tERK2'''</span>]] in [[A:spinal cord|<span style="color:#808000">spinal cord</span>]] associated with <span style="color:#FF0000">'''spinal cord'''</span>
 
|-
 
|-
 
|}
 
|}
Line 640: Line 640:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2007
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2007|2007]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Neurosci|BMC Neurosci]]
Line 660: Line 660:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulated</span>) of <span style="color:#800000">'''p38-MAPK'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulated</span>) of [[G:116590|<span style="color:#800000">'''p38-MAPK'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 671: Line 671:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
Line 692: Line 692:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulation</span>) of <span style="color:#800000">'''ERK1/2'''</span> in <span style="color:#808000">thoracic aorta</span> associated with <span style="color:#FF0000">'''diabetes mellitus'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulation</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]] in [[A:thoracic aorta|<span style="color:#808000">thoracic aorta</span>]] associated with <span style="color:#FF0000">'''diabetes mellitus'''</span>
 
|-
 
|-
 
|}
 
|}
Line 703: Line 703:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
Line 724: Line 724:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulation</span>) of <span style="color:#800000">'''p38-MAPK'''</span> in <span style="color:#808000">thoracic aorta</span> associated with <span style="color:#FF0000">'''diabetes mellitus'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulation</span>) of [[G:116590|<span style="color:#800000">'''p38-MAPK'''</span>]] in [[A:thoracic aorta|<span style="color:#808000">thoracic aorta</span>]] associated with <span style="color:#FF0000">'''diabetes mellitus'''</span>
 
|-
 
|-
 
|}
 
|}
Line 735: Line 735:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
Line 755: Line 755:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulated</span>) of <span style="color:#800000">'''ERK1/2'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulated</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 766: Line 766:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.22
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
Line 788: Line 788:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">regulated</span>) of <span style="color:#800000">'''ERK2'''</span>
+
[[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">regulated</span>) of [[G:116590|<span style="color:#800000">'''ERK2'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 799: Line 799:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.21
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.21
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Diabetes|Diabetes]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Diabetes|Diabetes]]
Line 819: Line 819:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (not) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affected</span>) of <span style="color:#800000">'''ERK1/2'''</span> in <span style="color:#808000">RVLM</span> associated with <span style="color:#FF0000">'''rostral ventrolateral medulla'''</span> and <span style="color:#FF0000">'''death'''</span>
+
|  Neg (not) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affected</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]] in [[A:RVLM|<span style="color:#808000">RVLM</span>]] associated with <span style="color:#FF0000">'''rostral ventrolateral medulla'''</span> and <span style="color:#FF0000">'''death'''</span>
 
|-
 
|-
 
|}
 
|}
Line 830: Line 830:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.21
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.21
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Biomed Sci|J Biomed Sci]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Biomed Sci|J Biomed Sci]]
Line 850: Line 850:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
|  Neg (without) <span style="color:#000080">'''Regulation'''</span> (<span style="color:#000080">affecting</span>) of <span style="color:#800000">'''ERK1/2'''</span> in <span style="color:#808000">sensory neurons</span> associated with <span style="color:#FF0000">'''stress'''</span>
+
|  Neg (without) [[E:Regulation|<span style="color:#000080">'''Regulation'''</span>]] (<span style="color:#000080">affecting</span>) of [[G:116590|<span style="color:#800000">'''ERK1/2'''</span>]] in [[A:sensory neurons|<span style="color:#808000">sensory neurons</span>]] associated with <span style="color:#FF0000">'''stress'''</span>
 
|-
 
|-
 
|}
 
|}
Line 861: Line 861:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.16
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.16
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Cardiovasc Diabetol|Cardiovasc Diabetol]]

Latest revision as of 13:31, 20 September 2012

Context Info
Confidence 0.49
First Reported 1995
Last Reported 2010
Negated 11
Speculated 4
Reported most in Body
Documents 25
Total Number 30
Disease Relevance 19.51
Pain Relevance 10.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) Golgi apparatus (Mapk1)
protein complex (Mapk1) microtubule organizing center (Mapk1) cytoplasm (Mapk1)
Anatomy Link Frequency
thoracic aorta 4
hippocampus 3
medulla 2
spinal cord 2
kidney cortex 2
Mapk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 235 100.00 Very High Very High Very High
Dopamine 113 99.98 Very High Very High Very High
Hippocampus 190 99.68 Very High Very High Very High
Spinal cord 256 99.66 Very High Very High Very High
Dorsal horn 56 99.16 Very High Very High Very High
Pain 435 99.06 Very High Very High Very High
Lasting pain 122 98.28 Very High Very High Very High
Rostral ventrolateral medulla 110 98.20 Very High Very High Very High
painful pain 28 97.24 Very High Very High Very High
allodynia 8 96.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 1422 99.92 Very High Very High Very High
Urological Neuroanatomy 13 99.80 Very High Very High Very High
Pain 587 99.06 Very High Very High Very High
Stress 32 98.66 Very High Very High Very High
Death 125 98.00 Very High Very High Very High
Apoptosis 14 96.80 Very High Very High Very High
Neuropathic Pain 61 96.24 Very High Very High Very High
Nervous System Injury 16 95.48 Very High Very High Very High
Frailty 8 94.40 High High
Pheochromocytoma 1 91.16 High High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quantification by ELISA revealed that the total ERK1/2 in ventrolateral medulla was not affected by microinjection of Mev into the bilateral RVLM (fig. 2).
Neg (not) Regulation (affected) of ERK1/2 in medulla associated with medulla and rostral ventrolateral medulla
1) Confidence 0.49 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.59 Pain Relevance 0.34
Therefore, the aim of the present series of experiments is to assess the spatial- and temporal-related changes in phosphorylation (activation) and protein expression of ERKs, mainly ERK1 and ERK2, in the spinal cord dorsal horn, SI area and hippocampus under both physiological pain (transient pain) and pathological pain (persistent pain) states.
Regulation (changes) of ERK2 in spinal cord dorsal horn associated with pain, lasting pain, dorsal horn, painful pain, hippocampus and spinal cord
2) Confidence 0.43 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 1.64 Pain Relevance 1.61
The extracellular signal-regulated kinase 1 and 2 (ERK) pathway, regulated by phosphorylation on specific amino acids, is emerging as an important signaling cascade in neurones, transducing sensory input into cellular responses.
Regulation (regulated) of extracellular signal-regulated kinase 1 and 2
3) Confidence 0.38 Published 2006 Journal Exp. Neurol. Section Abstract Doc Link 16513110 Disease Relevance 0.39 Pain Relevance 0.32
Under the present conditions fentanyl did not affect extracellular signal-regulated protein kinase 1 and 2, Stat and cyclic AMP-response element-binding protein activity.
Neg (not) Regulation (affect) of extracellular signal-regulated protein kinase 1 and 2
4) Confidence 0.34 Published 2003 Journal Neuroscience Section Abstract Doc Link 12535947 Disease Relevance 0 Pain Relevance 0.83
In this study, we examined the involvement of spinal ERK and p38 MAPK in each phase of i.t.
Spec (examined) Regulation (involvement) of p38 MAPK in spinal
5) Confidence 0.31 Published 2008 Journal Biol. Pharm. Bull. Section Abstract Doc Link 18520049 Disease Relevance 0.49 Pain Relevance 0.57
This also coincides with the biochemical hypothesis that dopamine affects ERK2 in the hippocampus via the NMDA-R.
Regulation (affects) of ERK2 in hippocampus associated with dopamine and hippocampus
6) Confidence 0.27 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762427 Disease Relevance 0.24 Pain Relevance 0.91
In contrast, the total ERK1/2 protein level was not affected by the treatment (Fig. 3D, upper panel).
Neg (not) Regulation (affected) of ERK1/2 in upper
7) Confidence 0.26 Published 2001 Journal BMC Cell Biol Section Body Doc Link PMC37242 Disease Relevance 0 Pain Relevance 0
Interestingly, the relative differences between ERK1 and ERK2 immunoreactivity were quite the same as that previous study (see the present results).
Regulation (immunoreactivity) of ERK2
8) Confidence 0.26 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 0.09 Pain Relevance 0.34
Combined differential participation of the spinal cord, SI area, and hippocampus in the multidimensional aspects of pain experience with region- and isoform-dependent responses of pERK1 and pERK2 to peripheral noxious stimulation observed in the present study, we propose a hypothesis that this differential activation of ERK1 and ERK2 across distinct regions under pain state might suggest the possibility for a different function of specific ERK members in the nociceptive processing and further provide a molecular basis for the differential involvement of individual components of nociceptive system in the diverse features of pain.
Spec (might) Regulation (responses) of pERK2 in hippocampus associated with nociception, pain, hippocampus and spinal cord
9) Confidence 0.26 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 1.01 Pain Relevance 1.01
However, the ERK2 enzyme seems to be more sensitive and exhibit stronger responses than ERK1 enzyme.
Regulation (sensitive) of ERK2
10) Confidence 0.26 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 0.25 Pain Relevance 0.58
There were no significant changes in total expression levels of ERK1 or ERK2 in ipsilateral hippocampus at any time point examined (data not shown).
Neg (no) Spec (examined) Regulation (changes) of ERK2 in hippocampus associated with hippocampus
11) Confidence 0.26 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 0.29 Pain Relevance 0.47
Quantitative blot immunolabeling techniques were used to determine the concentrations of ERK1 (M(r) 44 kDa) and ERK2 (M(r) 42 kDa), the two major extracellular signal-regulated protein kinases, in different regions of rat brain.
Regulation (concentrations) of ERK2 in brain
12) Confidence 0.25 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7532701 Disease Relevance 0 Pain Relevance 0.11
In spite of the great differences in basal expression amounts of total protein between ERK1 and ERK2 in the normal spinal cord, no significant alterations in tERK1 or tERK2 level were detected following noxious stimulation, transient or persistent, when compared to naïve rats, respectively (data not shown).
Neg (no) Regulation (alterations) of tERK2 in spinal cord associated with spinal cord
13) Confidence 0.22 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1949833 Disease Relevance 0.29 Pain Relevance 0.48
Three MAPK subfamilies have been well characterized: extracellular signal regulated kinase 1 and 2 (ERK1/2), c-jun N-terminal kinases (JNK) and p38-MAPK [7].
Regulation (regulated) of p38-MAPK
14) Confidence 0.22 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.20 Pain Relevance 0.04
We speculate a differential regulation of p38-MAPK and ERK1/2 in thoracic aorta and kidneys depending upon the duration and severity of diabetes.
Regulation (regulation) of ERK1/2 in thoracic aorta associated with diabetes mellitus
15) Confidence 0.22 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.13 Pain Relevance 0.07
We speculate a differential regulation of p38-MAPK and ERK1/2 in thoracic aorta and kidneys depending upon the duration and severity of diabetes.
Regulation (regulation) of p38-MAPK in thoracic aorta associated with diabetes mellitus
16) Confidence 0.22 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.07 Pain Relevance 0.07
Three MAPK subfamilies have been well characterized: extracellular signal regulated kinase 1 and 2 (ERK1/2), c-jun N-terminal kinases (JNK) and p38-MAPK [7].
Regulation (regulated) of ERK1/2
17) Confidence 0.22 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.19 Pain Relevance 0.04
Immunoreactivity was quantified by densitometry and compared with the extracellular signal–regulated kinase 2 (ERK2) signal in each sample to correct for differences in protein loading.


Regulation (regulated) of ERK2
18) Confidence 0.21 Published 2008 Journal Diabetes Section Body Doc Link PMC2551692 Disease Relevance 0.16 Pain Relevance 0.14
Results from ELISA showed that whereas the total ERK1/2 was not affected, augmented phosphorylation of ERK1/2 at Thr202 and Tyr204 in RVLM occurred preferentially during the pro-life phase of experimental brain stem death.
Neg (not) Regulation (affected) of ERK1/2 in RVLM associated with rostral ventrolateral medulla and death
19) Confidence 0.21 Published 2010 Journal J Biomed Sci Section Abstract Doc Link PMC2848001 Disease Relevance 0.71 Pain Relevance 0.27
A similar finding, though not directly related to the present study, was shown by Purves et al. [43] where they demonstrated using cultured sensory neurons that co-treatment with high glucose and oxidative stress results in an additive effect on p38-MAPK phosphorylation without affecting ERK1/2 activation.
Neg (without) Regulation (affecting) of ERK1/2 in sensory neurons associated with stress
20) Confidence 0.16 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0.93 Pain Relevance 0.03

[edit] General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox