INT49652

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Context Info
Confidence 0.67
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 10
Disease Relevance 6.23
Pain Relevance 4.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Fabp4) lipid particle (Fabp4) nucleus (Fabp4)
cytoplasm (Fabp4)
Anatomy Link Frequency
spinal 1
fat 1
adipocytes 1
Fabp4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
backache 516 100.00 Very High Very High Very High
Pain 120 98.40 Very High Very High Very High
Enkephalin 5 97.48 Very High Very High Very High
Spinal cord 1 82.40 Quite High
tetrodotoxin 1 79.76 Quite High
dexamethasone 5 58.20 Quite High
tolerance 15 38.60 Quite Low
metalloproteinase 15 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 532 100.00 Very High Very High Very High
Obesity 250 99.56 Very High Very High Very High
Pain 104 98.40 Very High Very High Very High
Hypertrophy 20 96.08 Very High Very High Very High
Hyperlipidemia 10 76.84 Quite High
Body Weight 30 69.92 Quite High
Diabetes Mellitus 20 64.32 Quite High
Impaired Glucose Tolerance 15 38.60 Quite Low
Hypertension 10 37.96 Quite Low
Cancer 16 36.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The terms used to present the details of research, in particular dependant variables such as ALBP, are important as they facilitate communication and common understanding.10 To further highlight the effect of definitional differences on ALBP prevalence, the studies identified in this review were categorized into three broad subgroups, according to their definitions, and the relative prevalence of ALBP between these groups was compared using period prevalence rates.
Gene_expression (prevalence) of ALBP associated with backache
1) Confidence 0.67 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004638 Disease Relevance 0.78 Pain Relevance 0.78
Diepenmaat et al28 defined ALBP as greater than four days per month of pain, and ignored any report of ALBP less than three days ALBP per month.
Gene_expression (defined) of ALBP associated with pain and backache
2) Confidence 0.67 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004638 Disease Relevance 1.73 Pain Relevance 1.73
Since the 1980s there has been an increasing appreciation of the extent of adolescent low back pain (ALBP) in the community.1–3 This shift in awareness appears to have resulted from a series of international epidemiological studies which identified a significant prevalence of reported spinal pain in otherwise ‘healthy’ adolescents.4–6
Gene_expression (appreciation) of ALBP in spinal associated with low back pain, pain and backache
3) Confidence 0.58 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004638 Disease Relevance 0.74 Pain Relevance 0.73
Defining ALBP
Gene_expression (Defining) of ALBP associated with backache
4) Confidence 0.58 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004638 Disease Relevance 1.03 Pain Relevance 1.03
The expression of aP2 (Primers: forward, 5'-AACACCGAGATTTCCTT-3' and reverse 5'-ACACATTCCACCAC-CAG-3') and PPAR?
Gene_expression (expression) of aP2
5) Confidence 0.52 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC3002919 Disease Relevance 0 Pain Relevance 0.03
Both aP2 and PPAR?
Gene_expression (Both) of aP2
6) Confidence 0.46 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC3002919 Disease Relevance 0.42 Pain Relevance 0
In the present study, the KCL group reduced accumulation of fat and mRNA expression of aP2 and PPAR?
Gene_expression (expression) of aP2 in fat
7) Confidence 0.46 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC3002919 Disease Relevance 0.47 Pain Relevance 0
and aP2 mRNA expression levels in adipocytes.



Gene_expression (expression) of aP2 mRNA in adipocytes associated with obesity
8) Confidence 0.41 Published 2010 Journal Lipids Health Dis Section Abstract Doc Link PMC3002919 Disease Relevance 0.29 Pain Relevance 0
and aP2 mRNA expression levels.
Gene_expression (expression) of aP2 mRNA
9) Confidence 0.41 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC3002919 Disease Relevance 0.77 Pain Relevance 0
Several well characterized cis-elements, including AP2, CREB, NF1, and NFkB, reside on this region of the rENK gene.
Gene_expression (reside) of AP2
10) Confidence 0.17 Published 1995 Journal Mol. Neurobiol. Section Abstract Doc Link 7576307 Disease Relevance 0 Pain Relevance 0.31

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