INT49723

From wiki-pain
Revision as of 19:49, 24 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 1993
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.67
Pain Relevance 2.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (GLUL) small molecule metabolic process (GLUL) lyase activity (GLUL)
Golgi apparatus (GLUL) intracellular (GLUL) ligase activity (GLUL)
Anatomy Link Frequency
platelet 1
GLUL (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 15 100.00 Very High Very High Very High
gABA 9 100.00 Very High Very High Very High
tetrodotoxin 8 100.00 Very High Very High Very High
Dopamine 8 95.60 Very High Very High Very High
halothane 1 88.08 High High
antagonist 8 84.48 Quite High
Substantia nigra 2 77.56 Quite High
agonist 32 75.80 Quite High
Serotonin 21 5.68 Low Low
Potency 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhage 23 92.12 High High
Injury 1 91.44 High High
Syndrome 20 79.32 Quite High
Generaliased Trisomy 1 70.40 Quite High
Epilepsy 1 58.80 Quite High
Muscle Hypotonia 1 58.00 Quite High
Convulsion 1 57.12 Quite High
Intellectual Impairment 1 56.08 Quite High
Tremor 1 54.48 Quite High
Psychosis 1 53.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
s polymorphism presenting with platelet Gs hyperfunction, brachydactyly, increased alkaline phosphatase and neurological problems or growth deficiency [9, 17].
Localization (presenting) of Gs in platelet
1) Confidence 0.27 Published 2007 Journal Eur J Pediatr Section Body Doc Link PMC2042511 Disease Relevance 0.67 Pain Relevance 0.08
Replacing the second (i2) or third intracellular loop (i3) of Rs1 eliminated both Gs and Gq signaling (Figure S3).
Localization (eliminated) of Gs
2) Confidence 0.16 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2267039 Disease Relevance 0 Pain Relevance 0.04
L-dopa induces Ca(2+)-dependent and tetrodotoxin-sensitive release of endogenous glutamate from rat striatal slices.
Localization (release) of glutamate associated with tetrodotoxin and glutamate
3) Confidence 0.00 Published 1993 Journal Brain Res. Section Title Doc Link 8104083 Disease Relevance 0 Pain Relevance 0.54
L-DOPA (10-1000 microM) concentration-dependently released glutamate (Glu) from superfused rat striatal slices.
Localization (released) of glutamate associated with glutamate
4) Confidence 0.00 Published 1993 Journal Brain Res. Section Abstract Doc Link 8104083 Disease Relevance 0 Pain Relevance 0.47
Extracellular levels of glutamate (GLU) and taurine (TAU) were not modified by IC stimulation, TTX or 0 Ca2+ although high K+ promoted GABA and TAU release but not that of GLU.
Localization (release) of glutamate associated with tetrodotoxin, gaba and glutamate
5) Confidence 0.00 Published 1995 Journal Brain Res. Section Abstract Doc Link 7583219 Disease Relevance 0 Pain Relevance 0.98

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox