INT50530

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Context Info
Confidence 0.17
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.88
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (MDFIC) nucleolus (MDFIC) nucleus (MDFIC)
transcription factor binding (MDFIC) cytoplasm (MDFIC)
MDFIC (Homo sapiens)
Pain Link Frequency Relevance Heat
Endep 2 97.74 Very High Very High Very High
fluoxetine 1 97.10 Very High Very High Very High
antidepressant 2 96.54 Very High Very High Very High
fibrosis 8 84.04 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Parenteral administration 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 98.44 Very High Very High Very High
Sickle Cell Anemia 86 98.40 Very High Very High Very High
Thalassemia 36 96.84 Very High Very High Very High
Pseudolymphoma 1 95.08 Very High Very High Very High
Iron Overload 48 93.76 High High
Fibrosis 1 84.04 Quite High
Hepatitis Virus Infection 3 82.36 Quite High
Cirrhosis 8 80.16 Quite High
Hyperplasia 1 75.00 Quite High
Myelodysplastic Syndromes 2 53.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND: Cutaneous pseudolymphomas were encountered in eight patients who were receiving the antidepressant (AD) medications fluoxetine hydrochloride and amitriptyline hydrochloride, which promote tumor growth and suppress certain lymphoid functions by inhibiting the binding of endogenous histamine to an intracellular histamine receptor designated HIC.
HIC Binding (binding) of associated with antidepressant, pseudolymphoma, cancer, endep and fluoxetine
1) Confidence 0.17 Published 1995 Journal Arch Dermatol Section Abstract Doc Link 7632065 Disease Relevance 0.27 Pain Relevance 0.23
ng/mL are associated with HIC >10?
HIC Binding (associated) of
2) Confidence 0.03 Published 2010 Journal Advances in Hematology Section Body Doc Link PMC2872757 Disease Relevance 1.61 Pain Relevance 0.14

General Comments

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