INT52114

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Context Info
Confidence 0.05
First Reported 1995
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprd1, ADCY1) small molecule metabolic process (ADCY1) GTPase activity (ADCY1)
transmembrane transport (ADCY1) cytoplasm (Oprd1) signal transducer activity (Oprd1)
Oprd1 (Rattus norvegicus)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 11 100.00 Very High Very High Very High
narcan 2 99.58 Very High Very High Very High
Immobilon 7 99.04 Very High Very High Very High
addiction 2 98.00 Very High Very High Very High
antagonist 2 86.72 High High
Enkephalin 1 72.92 Quite High
Analgesic 1 65.60 Quite High
agonist 1 39.88 Quite Low
Disease Link Frequency Relevance Heat
Neuroblastoma 2 98.84 Very High Very High Very High
Bordatella Infection 6 87.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To find out the reason of weak addiction property of dihydroetorphine, we compared the affinities of dihydroetorphine to the type selective opioid receptor and inhibition effect on the adenylyl cyclase activity with those of etorphine.
opioid receptor Regulation (effect) of adenylyl cyclase associated with addiction, opioid receptor and immobilon
1) Confidence 0.05 Published 1995 Journal Life Sci. Section Abstract Doc Link 7739347 Disease Relevance 0 Pain Relevance 0.49
Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells.
opioid receptor Regulation (regulation) of adenylyl cyclase associated with neuroblastoma, narcan and opioid receptor
2) Confidence 0.00 Published 2006 Journal Mol. Pharmacol. Section Title Doc Link 16525132 Disease Relevance 0.46 Pain Relevance 0.41

General Comments

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