INT53222

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Context Info
Confidence 0.26
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (C5AR1) plasma membrane (C5AR1) signal transducer activity (C5AR1)
C5AR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
neuralgia 1 95.76 Very High Very High Very High
Inflammation 1 70.60 Quite High
Disease Link Frequency Relevance Heat
Herpes Zoster 2 97.32 Very High Very High Very High
Neuralgia 1 95.76 Very High Very High Very High
Herpes Simplex Virus Infection 2 95.36 Very High Very High Very High
Herpes Simplex Virus 1 78.28 Quite High
INFLAMMATION 1 70.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism of action seems to be associated with the inhibition of local anaphylatoxin release (C3a and C5a) which are responsible for the acute evolution of the lesions produced by viruses of the Zoster-Varicella group and with a quick lethal effect on the parasitized cells which are selectively eliminated without affecting the adjoining normal cells of the host.
Regulation (responsible) of Negative_regulation (inhibition) of C5a associated with herpes zoster
1) Confidence 0.26 Published 1993 Journal Roum Arch Microbiol Immunol Section Abstract Doc Link 7827366 Disease Relevance 0.61 Pain Relevance 0.13

General Comments

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