INT53505

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Context Info
Confidence 0.33
First Reported 1994
Last Reported 2010
Negated 1
Speculated 2
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 1.33
Pain Relevance 2.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CASP4) intracellular (CASP4)
Anatomy Link Frequency
urine 3
plasma 2
CASP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 209 99.32 Very High Very High Very High
dexamethasone 2 96.80 Very High Very High Very High
antagonist 1 92.80 High High
cINOD 132 86.68 High High
Inflammation 10 85.04 High High
headache 3 72.24 Quite High
corticosteroid 1 54.96 Quite High
Arthritis 8 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 3 100.00 Very High Very High Very High
Apoptosis 7 98.72 Very High Very High Very High
Cv General 2 Under Development 1 86.48 High High
INFLAMMATION 18 85.04 High High
Adhesions 1 81.28 Quite High
Pulmonary Hypertension 1 80.08 Quite High
Fever 4 73.64 Quite High
Vomiting 5 72.68 Quite High
Headache 3 72.24 Quite High
Syndrome 1 66.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As expected, the non-compliant group showed no significant effect of treatment assignment on either urine Tx-M or PGI-M concentrations (P>0.05 for both).
Neg (no) Regulation (effect) of Tx-M in urine
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824826 Disease Relevance 0 Pain Relevance 0.47
We undertook analyses of urine and plasma samples from ADAPT participants to determine whether naproxen or celecoxib treatment in individuals 70 years or older produced changes in urine Tx-M and PGI-M levels that were similar to findings reported previously in younger individuals.
Spec (whether) Regulation (changes) of Tx-M in urine
2) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824826 Disease Relevance 0 Pain Relevance 0.63
Our results showed that, similar to results reported from younger cohorts, ADAPT participants who were compliant with their assigned treatment regimen showed expected changes in urine Tx-M and PGI-M, but not in plasma or urine F2-IsoPs.
Regulation (changes) of Tx-M in urine
3) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824826 Disease Relevance 0 Pain Relevance 0.42
We undertook analyses of urine and plasma samples from ADAPT participants to determine whether naproxen or celecoxib treatment in individuals 70 years or older produced changes in urine Tx-M and PGI-M levels that were similar to findings reported previously in younger individuals.
Spec (whether) Regulation (changes) of Tx-M in plasma
4) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824826 Disease Relevance 0 Pain Relevance 0.63
Granzyme B, caspase 3, lamin A/C, caspase 10 and caspase 4 were all up regulated.
Regulation (regulated) of caspase 4
5) Confidence 0.03 Published 2007 Journal Virol J Section Body Doc Link PMC2042503 Disease Relevance 0.61 Pain Relevance 0.08
Oxygent HT-induced changes in mPAP, flush, and plasma TxB were blocked by aspirin and ibuprofen.
Regulation (changes) of TxB in plasma associated with aspirin and increased venous pressure under development
6) Confidence 0.00 Published 1994 Journal Artif Cells Blood Substit Immobil Biotechnol Section Abstract Doc Link 7849964 Disease Relevance 0.72 Pain Relevance 0.29

General Comments

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