INT53854

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Context Info
Confidence 0.44
First Reported 1994
Last Reported 2007
Negated 3
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Uts2) extracellular region (Uts2)
Anatomy Link Frequency
ileum 3
bladder 1
Uts2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 98.12 Very High Very High Very High
Somatostatin 2 97.40 Very High Very High Very High
anesthesia 1 10.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In both the frog bladder and ileum preparations, the effect of urotensin II was not affected by preincubation of the strips with atropine, tetrodotoxin, and somatostatin-14 but indomethacin produced a significant (P < 0.05) decrease in the strength of the contractions of the bladder (to 21 +/- 6% of control values) and ileum (to 32 +/- 13%).
Neg (not) Regulation (affected) of Negative_regulation (effect) of urotensin II in ileum associated with tetrodotoxin and somatostatin
1) Confidence 0.44 Published 1994 Journal Gen. Comp. Endocrinol. Section Abstract Doc Link 7883148 Disease Relevance 0 Pain Relevance 0.15
Pretreatment with NG-nitro-L-arginine methyl ester (L-NAME) 100 micromol/L did not affect the inhibitory effects of UII (300 nmol/L) on the CSB.
Neg (not) Regulation (affect) of Negative_regulation (effects) of UII
2) Confidence 0.24 Published 2007 Journal Acta Pharmacol. Sin. Section Body Doc Link 17241524 Disease Relevance 0 Pain Relevance 0
In both the frog bladder and ileum preparations, the effect of urotensin II was not affected by preincubation of the strips with atropine, tetrodotoxin, and somatostatin-14 but indomethacin produced a significant (P < 0.05) decrease in the strength of the contractions of the bladder (to 21 +/- 6% of control values) and ileum (to 32 +/- 13%).
Neg (not) Regulation (affected) of in bladder Negative_regulation (effect) of urotensin II in ileum associated with tetrodotoxin and somatostatin
3) Confidence 0.15 Published 1994 Journal Gen. Comp. Endocrinol. Section Abstract Doc Link 7883148 Disease Relevance 0 Pain Relevance 0.15

General Comments

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