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Context Info
Confidence 0.34
First Reported 1993
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Gnai1) GTPase activity (Gnai1) cytoplasm (Gnai1)
signal transducer activity (Gnai1) signal transduction (Gnai1) nucleus (Gnai1)
Gnai1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 1 99.16 Very High Very High Very High
Pain threshold 2 98.48 Very High Very High Very High
Antihistamine 4 94.56 High High
antinociception 5 93.68 High High
agonist 2 92.48 High High
Potency 1 91.20 High High
Antinociceptive 2 89.96 High High
Opioid 4 87.32 High High
Morphine 1 85.88 High High
tail-flick 1 78.64 Quite High
Disease Link Frequency Relevance Heat
Pain 2 98.48 Very High Very High Very High
Urological Neuroanatomy 1 98.40 Very High Very High Very High
Bordatella Infection 1 80.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment with anti-Gi alpha(1) (12.5 microg per mouse i.c.v.), anti-Gi alpha(2) (25 microg per mouse i.c.v.) and anti-Gi alpha(3) (25 microg per mouse i.c.v.), administered 24 and 18 h before test, prevented the antihistamine-induced antinociception.
anti-Gi alpha Binding (Pretreatment) of associated with antinociception and antihistamine
1) Confidence 0.34 Published 2002 Journal Neuroscience Section Abstract Doc Link 11927163 Disease Relevance 0.10 Pain Relevance 0.57
Anti-Gi2 alpha and anti-Gx/z alpha, but not anti-Gi1 alpha, reduced the specific binding of [3H]DAMGO to the opioid receptor in PAG.
anti-Gi1 alpha Binding (binding) of associated with urological neuroanatomy and opioid receptor
2) Confidence 0.05 Published 1993 Journal Life Sci. Section Abstract Doc Link 7902522 Disease Relevance 0.18 Pain Relevance 0.90

General Comments

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