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Context Info
Confidence 0.48
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.02
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) signal transduction (GNRH1) extracellular space (GNRH1)
extracellular region (GNRH1) plasma membrane (FSHR) signal transducer activity (FSHR)
GNRH1 (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 5 98.24 Very High Very High Very High
Clonidine 2 86.72 High High
Endogenous opioid 2 75.00 Quite High
antagonist 2 67.40 Quite High
opiate 1 66.96 Quite High
Dismenorea 1 23.92 Low Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 20 98.90 Very High Very High Very High
Polycystic Ovary Syndrome 52 98.80 Very High Very High Very High
Syndrome 11 93.88 High High
Empty Sella Syndrome 1 83.92 Quite High
Reprotox - General 2 3 75.00 Quite High
Hyperinsulinism 4 53.44 Quite High
Acanthosis 1 52.08 Quite High
Alopecia 7 50.84 Quite High
Acne 1 49.76 Quite Low
Hirsutism 26 49.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both groups showed equivalent elevations in LH (fourfold to sixfold) in response to GnRH stimulation, but obese patients had significantly lower basal (p < 0.05) and GnRH-stimulated (p < 0.01) FSH levels.
GnRH Positive_regulation (stimulated) of FSH associated with obesity
1) Confidence 0.48 Published 1994 Journal Brain Res. Bull. Section Abstract Doc Link 7922600 Disease Relevance 0.89 Pain Relevance 0.43
However, their basal and GnRH-stimulated FSH concentrations were normal.
GnRH Positive_regulation (stimulated) of FSH
2) Confidence 0.37 Published 1998 Journal Metab. Clin. Exp. Section Abstract Doc Link 9826209 Disease Relevance 0.39 Pain Relevance 0.09
High GnRH expression increases LH and low GnRH increases FSH synthesis.
GnRH Positive_regulation (increases) of FSH
3) Confidence 0.05 Published 2010 Journal International Journal of Trichology Section Body Doc Link PMC3002408 Disease Relevance 0.75 Pain Relevance 0.03

General Comments

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