INT55502

Context Info Confidence 0.00 First Reported 1994 Last Reported 1994 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.08

transport (NDUFC1, Nox1) endosome (Nox1) mitochondrion (NDUFC1) small molecule metabolic process (NDUFC1) extracellular matrix organization (Nox1) response to stress (Nox1)

NDUFC1 (Homo sapiens) Nox1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat antiarrhythmic agent 2 93.40 lidocaine 1 47.76

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The results indicate that BRB-I-28 and its derivatives have concentration-dependent inhibitory effects on NADH oxidase and NADH-CoQ reductase (complex I), but they have no significant effects on succinate oxidase, succinate dehydrogenase (complex II), CoQ-cytochrome c reductase (complex III), cytochrome c oxidase (complex IV), and NADH-K3Fe(CN)6 reductase.

complex I Regulation (effects) of NADH oxidase

1) Confidence 0.00 Published 1994 Journal Res. Commun. Mol. Pathol. Pharmacol. Section Abstract Doc Link 7994564 Disease Relevance 0 Pain Relevance 0.08

General Comments

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