INT57290

Context Info Confidence 0.69 First Reported 1994 Last Reported 1994 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 3 Disease Relevance 2.09 Pain Relevance 1.57

extracellular space (IL17B) extracellular region (IL17B) cell-cell signaling (IL17B)

Anatomy Link Frequency bladder 1 IL17B (Homo sapiens)

Pain Link Frequency Relevance Heat interstitial cystitis 12 99.64 cytokine 12 85.04 Inflammatory response 3 73.08

Disease Link Frequency Relevance Heat Bladder Cancer 3 99.76 Interstitial Cystitis 12 99.64 Cystitis 3 98.48 Bladder Disease 6 97.76 INFLAMMATION 3 72.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The normal and interstitial cystitis groups showed no interleukin-1b elevation.

Neg (no) Positive_regulation (elevation) of interleukin-1b associated with interstitial cystitis

1) Confidence 0.69 Published 1994 Journal J. Urol. Section Abstract Doc Link 8158759 Disease Relevance 0.68 Pain Relevance 0.51

Significant elevation of urinary interleukin-1b was found in patients with bacterial cystitis compared to the interstitial cystitis and control groups (p < 0.001).

Positive_regulation (elevation) of interleukin-1b associated with cystitis and interstitial cystitis

2) Confidence 0.69 Published 1994 Journal J. Urol. Section Abstract Doc Link 8158759 Disease Relevance 0.70 Pain Relevance 0.52

Of the patients with bladder tumors 58% showed elevation of urinary interleukin-1b (p < 0.001).

Positive_regulation (elevation) of interleukin-1b in bladder associated with bladder cancer

3) Confidence 0.69 Published 1994 Journal J. Urol. Section Abstract Doc Link 8158759 Disease Relevance 0.71 Pain Relevance 0.54

General Comments

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