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Context Info
Confidence 0.00
First Reported 1993
Last Reported 1993
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Trim13) intracellular (Trim13) ligase activity (Trim13)
cytoplasm (Trim13) signal transducer activity (Trim13) signal transduction (Trim13)
Trim13 (Mus musculus)
Atxn2l (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 5 100.00 Very High Very High Very High
agonist 8 99.56 Very High Very High Very High
opioid receptor 5 94.68 High High
antagonist 3 88.64 High High
Pain 1 78.64 Quite High
Neurotransmitter 1 75.68 Quite High
Endogenous opioid 1 74.24 Quite High
MU agonist 1 72.32 Quite High
Buprenorphine 1 69.12 Quite High
mu opioid receptor 1 64.88 Quite High
Disease Link Frequency Relevance Heat
Pain 2 78.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The D95N mutant receptor had reduced affinity for delta receptor-selective agonists such as enkephalin, [D-Pen2,D-Pen5]enkephalin and [D-Ser2,Leu5]enkephalin-Thr6 such that it did not bind these peptides even at micromolar concentrations.
Leu5 Neg (not) Binding (bind) of D-Pen2 associated with agonist and enkephalin
1) Confidence 0.00 Published 1993 Journal J. Biol. Chem. Section Abstract Doc Link 8226821 Disease Relevance 0.08 Pain Relevance 1.17

General Comments

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