INT59443

Context Info Confidence 0.06 First Reported 1993 Last Reported 1993 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.39

RNA binding (Gtf3a) nucleus (Gtf3a) intracellular (Gtf3a) plasma membrane (Oprd1) DNA binding (Gtf3a) cytoplasm (Oprd1)

Anatomy Link Frequency nervous system 1 Oprd1 (Rattus norvegicus) Gtf3a (Rattus norvegicus)

Pain Link Frequency Relevance Heat Opioid 3 100.00 opioid receptor 2 100.00 Enkephalin 2 99.64 antagonist 1 46.96

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The zeta (zeta) opioid receptor mediates the activity of the opioid growth factor, [Met5]-enkephalin, a peptide that regulates developmental events in a variety of normal and tumorigenic tissues and cells, including the nervous system.

opioid receptor Positive_regulation (mediates) of factor in nervous system associated with enkephalin, opioid receptor and opioid

1) Confidence 0.06 Published 1993 Journal Brain Res. Section Abstract Doc Link 8385541 Disease Relevance 0 Pain Relevance 0.39

General Comments

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