INT59742

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Context Info
Confidence 0.27
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.41

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extracellular space (Npy) extracellular region (Npy) plasma membrane (Glp1r)
signal transducer activity (Glp1r)
Glp1r (Rattus norvegicus)
Npy (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 2 90.00 High High
Clonidine 2 89.36 High High
Neuropeptide 4 75.00 Quite High
Disease Link Frequency Relevance Heat
Hypoglycemia 4 81.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The glucagon-like peptide-I-(7-36) amide (GLP-1), a known gluco-incretin in humans, induced at low concentration (10(-9) M) a similar expression of NPY mRNA and peptide secretion in INS-1 cells.
GLP-1 Positive_regulation (induced) of Gene_expression (expression) of NPY
1) Confidence 0.27 Published 1993 Journal Endocrinology Section Abstract Doc Link 8396008 Disease Relevance 0.16 Pain Relevance 0.20
The glucagon-like peptide-I-(7-36) amide (GLP-1), a known gluco-incretin in humans, induced at low concentration (10(-9) M) a similar expression of NPY mRNA and peptide secretion in INS-1 cells.
gluco-incretin Positive_regulation (induced) of Gene_expression (expression) of NPY
2) Confidence 0.23 Published 1993 Journal Endocrinology Section Abstract Doc Link 8396008 Disease Relevance 0.16 Pain Relevance 0.20

General Comments

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