INT60759

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Context Info
Confidence 0.01
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ikbip) plasma membrane (Oprd1) cytoplasm (Oprd1)
signal transducer activity (Oprd1)
Anatomy Link Frequency
myocytes 2
Ikbip (Rattus norvegicus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 6 100.00 Very High Very High Very High
Opioid 4 100.00 Very High Very High Very High
Dynorphin 1 73.12 Quite High
Kinase C inhibitor 1 61.52 Quite High
Enkephalin 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phorbol ester-induced increase in prodynorphin gene transcription was prevented by pretreatment of myocytes or isolated nuclei with staurosporine, suggesting that myocardial opioid gene expression may be regulated by nuclear protein kinase C.
nuclear protein kinase Regulation (regulated) of Gene_expression (expression) of myocardial opioid gene in myocytes associated with kinase c and opioid
1) Confidence 0.01 Published 1995 Journal J. Biol. Chem. Section Abstract Doc Link 8530417 Disease Relevance 0 Pain Relevance 0.52

General Comments

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