INT61134

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(Generated page)
 
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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1996
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:1996|1996]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 48: Line 48:
 
fontcolor=white,
 
fontcolor=white,
 
label="IL10",
 
label="IL10",
URL="IL10"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:3586"
 
];
 
];
 
node2
 
node2
Line 55: Line 55:
 
style=filled,
 
style=filled,
 
fillcolor=yellow,
 
fillcolor=yellow,
URL=Negative_regulation
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Negative_regulation"
 
];
 
];
 
node3
 
node3
Line 62: Line 62:
 
fillcolor=green,
 
fillcolor=green,
 
label="Gene\nexpression",
 
label="Gene\nexpression",
URL=Gene_expression
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Gene_expression"
 
];
 
];
 
node4
 
node4
Line 70: Line 70:
 
fontcolor=white,
 
fontcolor=white,
 
label="IL1B",
 
label="IL1B",
URL="IL1B"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:3553"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 90: Line 90:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[cell-cell signaling]] ([[IL10]], [[IL1B]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:cell-cell signaling|cell-cell signaling]] ([[G:3586|IL10]], [[G:3553|IL1B]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular space]] ([[IL10]], [[IL1B]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular space|extracellular space]] ([[G:3586|IL10]], [[G:3553|IL1B]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[extracellular region]] ([[IL10]], [[IL1B]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:extracellular region|extracellular region]] ([[G:3586|IL10]], [[G:3553|IL1B]])
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[aging]] ([[IL1B]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:aging|aging]] ([[G:3553|IL1B]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[intracellular]] ([[IL10]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:intracellular|intracellular]] ([[G:3586|IL10]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[response to stress]] ([[IL10]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:response to stress|response to stress]] ([[G:3586|IL10]])
 
|-
 
|-
 
|}
 
|}
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{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:38|blood]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:blood|blood]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:372|cartilage]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:cartilage|cartilage]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:216|CSF]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:CSF|CSF]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cytokine]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cytokine|cytokine]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Spinal cord]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Spinal cord|Spinal cord]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 92.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[intrathecal]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:intrathecal|intrathecal]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[headache]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:headache|headache]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Osteoarthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Osteoarthritis|Osteoarthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 37
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 37
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[allodynia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:allodynia|allodynia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 83.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Thermal hyperalgesia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Thermal hyperalgesia|Thermal hyperalgesia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Eae]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Eae|Eae]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 71.76
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 71.76
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:INFLAMMATION|INFLAMMATION]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cancer]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Cancer|Cancer]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Necrosis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Necrosis|Necrosis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Headache]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Headache|Headache]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 90.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Chills]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Chills|Chills]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.88
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.88
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Knee Osteoarthritis]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Knee Osteoarthritis|Knee Osteoarthritis]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Fever]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Fever|Fever]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Syndrome]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Syndrome|Syndrome]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.48
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.28
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Injury]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Injury|Injury]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 3
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.12
Line 271: Line 271:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''rhIL-10'''</span> <span style="color:#000080">'''Negative_regulation'''</span> (<span style="color:#000080">suppressed</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">synthesis</span>) of <span style="color:#800000">'''IL-1'''</span> in <span style="color:#808000">blood</span> associated with <span style="color:#FF0000">'''necrosis'''</span>, <span style="color:#FF0000">'''inflammation'''</span>, <span style="color:#FF0000">'''cancer'''</span> and <span style="color:#FF0000">'''cytokine'''</span>
+
|  [[G:3586|<span style="color:#800000">'''rhIL-10'''</span>]] [[E:Negative_regulation|<span style="color:#000080">'''Negative_regulation'''</span>]] (<span style="color:#000080">suppressed</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">synthesis</span>) of [[G:3553|<span style="color:#800000">'''IL-1'''</span>]] in [[A:blood|<span style="color:#808000">blood</span>]] associated with <span style="color:#FF0000">'''necrosis'''</span>, <span style="color:#FF0000">'''inflammation'''</span>, <span style="color:#FF0000">'''cancer'''</span> and <span style="color:#FF0000">'''cytokine'''</span>
 
|-
 
|-
 
|}
 
|}
Line 282: Line 282:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.46
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.46
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1996
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:1996|1996]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Blood|Blood]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Blood|Blood]]
Line 302: Line 302:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''IL10'''</span> <span style="color:#000080">'''Negative_regulation'''</span> (<span style="color:#000080">lowered</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">levels</span>) of <span style="color:#800000">'''IL-1'''</span> in <span style="color:#808000">CSF</span> associated with <span style="color:#FF0000">'''inflammation'''</span>
+
|  [[G:3586|<span style="color:#800000">'''IL10'''</span>]] [[E:Negative_regulation|<span style="color:#000080">'''Negative_regulation'''</span>]] (<span style="color:#000080">lowered</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">levels</span>) of [[G:3553|<span style="color:#800000">'''IL-1'''</span>]] in [[A:CSF|<span style="color:#808000">CSF</span>]] associated with <span style="color:#FF0000">'''inflammation'''</span>
 
|-
 
|-
 
|}
 
|}
Line 313: Line 313:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.13
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.13
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Eur. J. Neurosci.|Eur. J. Neurosci.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Eur. J. Neurosci.|Eur. J. Neurosci.]]
Line 333: Line 333:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''IL-10'''</span> <span style="color:#000080">'''Negative_regulation'''</span> (<span style="color:#000080">reducing</span>) of <span style="color:#000080">'''Gene_expression'''</span> (<span style="color:#000080">expression</span>) of <span style="color:#800000">'''IL-1'''</span> in <span style="color:#808000">cartilage</span>
+
|  [[G:3586|<span style="color:#800000">'''IL-10'''</span>]] [[E:Negative_regulation|<span style="color:#000080">'''Negative_regulation'''</span>]] (<span style="color:#000080">reducing</span>) of [[E:Gene_expression|<span style="color:#000080">'''Gene_expression'''</span>]] (<span style="color:#000080">expression</span>) of [[G:3553|<span style="color:#800000">'''IL-1'''</span>]] in [[A:cartilage|<span style="color:#808000">cartilage</span>]]
 
|-
 
|-
 
|}
 
|}
Line 344: Line 344:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.06
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.06
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Musculoskelet Disord|BMC Musculoskelet Disord]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:BMC Musculoskelet Disord|BMC Musculoskelet Disord]]

Latest revision as of 08:39, 20 September 2012

Context Info
Confidence 0.46
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.13
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (IL10, IL1B) extracellular space (IL10, IL1B) extracellular region (IL10, IL1B)
aging (IL1B) intracellular (IL10) response to stress (IL10)
Anatomy Link Frequency
blood 2
cartilage 2
CSF 2
IL10 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 100.00 Very High Very High Very High
Inflammation 4 100.00 Very High Very High Very High
Spinal cord 2 92.32 High High
intrathecal 3 90.40 High High
headache 1 90.28 High High
Osteoarthritis 37 89.80 High High
Pain 10 88.28 High High
allodynia 2 83.60 Quite High
Thermal hyperalgesia 2 82.60 Quite High
Eae 1 71.76 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 100.00 Very High Very High Very High
Cancer 2 99.60 Very High Very High Very High
Necrosis 3 99.36 Very High Very High Very High
Headache 1 90.28 High High
Chills 1 89.88 High High
Knee Osteoarthritis 36 89.80 High High
Fever 1 89.40 High High
Syndrome 1 88.48 High High
Pain 7 88.28 High High
Injury 3 86.12 High High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dose-related effects of rhIL-10 included transient increases of circulating neutrophils and monocytes and decreases of lymphocytes. rhIL-10 markedly suppressed, in a time- and dose-dependent manner, the synthesis of the inflammatory cytokines IL-1 beta and tumor necrosis factor alpha by whole blood stimulated ex vivo with bacterial lipopolysaccharide.
rhIL-10 Negative_regulation (suppressed) of Gene_expression (synthesis) of IL-1 in blood associated with necrosis, inflammation, cancer and cytokine
1) Confidence 0.46 Published 1996 Journal Blood Section Abstract Doc Link 8555493 Disease Relevance 0.66 Pain Relevance 0.19
In keeping with IL-10's known anti-inflammatory actions, AD-h-IL10 lowered CSF levels of IL-1, relative to control AD.
IL10 Negative_regulation (lowered) of Gene_expression (levels) of IL-1 in CSF associated with inflammation
2) Confidence 0.13 Published 2005 Journal Eur. J. Neurosci. Section Abstract Doc Link 15869510 Disease Relevance 0.97 Pain Relevance 1.22
On one side, IL-10 has proanabolic effects, such as promotion of proteoglycan synthesis by human chondrocytes "in vitro" [17], prevention of cartilage destruction by reducing IL-1 and TNF-alpha mRNA expression in articular chondrocytes [17]; on the other side, IL-10 may also exert procatabolic effects as in human fibroblasts it down-regulates type I collagen mRNA expression and enhances collagenase and stromelysin gene expression [18].
IL-10 Negative_regulation (reducing) of Gene_expression (expression) of IL-1 in cartilage
3) Confidence 0.06 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2268688 Disease Relevance 0.51 Pain Relevance 0.23

[edit] General Comments

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