INT61347

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Context Info
Confidence 0.49
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.06
Pain Relevance 3.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (GAL) Golgi apparatus (GAL) cellular_component (GAL)
response to stress (GAL) cytoplasm (GAL)
GAL (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 54 100.00 Very High Very High Very High
Neuropeptide 238 99.52 Very High Very High Very High
medulla 2 98.28 Very High Very High Very High
Neurotransmitter 30 97.28 Very High Very High Very High
Pain 10 97.20 Very High Very High Very High
Catecholamine 6 96.56 Very High Very High Very High
substance P 2 94.08 High High
Delta opioid receptors 6 92.16 High High
Opioid 7 88.56 High High
Somatostatin 3 74.88 Quite High
Disease Link Frequency Relevance Heat
Stress 8 99.98 Very High Very High Very High
Pain 10 97.20 Very High Very High Very High
Hypertension 4 66.40 Quite High
Disease 18 5.00 Very Low Very Low Very Low
Pheochromocytoma 8 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate the possible mechanism leading to the decrease in GH secretion by specific activation of delta-opioidergic pathway in man, we compared, in normal subjects, the effect of DT on GH secretion responses to two different GH secretagogues, namely arginine (ARG) and galanin (GAL).
Positive_regulation (responses) of Localization (secretagogues) of GAL
1) Confidence 0.49 Published 1995 Journal Regul. Pept. Section Abstract Doc Link 8570858 Disease Relevance 0 Pain Relevance 0.21
To investigate the possible mechanism leading to the decrease in GH secretion by specific activation of delta-opioidergic pathway in man, we compared, in normal subjects, the effect of DT on GH secretion responses to two different GH secretagogues, namely arginine (ARG) and galanin (GAL).
Positive_regulation (responses) of Localization (secretagogues) of galanin
2) Confidence 0.49 Published 1995 Journal Regul. Pept. Section Abstract Doc Link 8570858 Disease Relevance 0 Pain Relevance 0.21
To investigate the possible mechanism leading to the decrease in GH secretion by specific activation of delta-opioidergic pathway in man, we compared, in normal subjects, the effect of DT on GH secretion responses to two different GH secretagogues, namely arginine (ARG) and galanin (GAL).
Positive_regulation (responses) of Localization (secretion) of GAL
3) Confidence 0.49 Published 1995 Journal Regul. Pept. Section Abstract Doc Link 8570858 Disease Relevance 0 Pain Relevance 0.21
Stress induces the secretion of enkephalins, catestatin, NPY, VIP, galanin, and other neuropeptides (23–26).
Positive_regulation (induces) of Localization (secretion) of galanin associated with stress, neuropeptide and enkephalin
4) Confidence 0.12 Published 2010 Journal AAPS J Section Body Doc Link PMC2976990 Disease Relevance 1.06 Pain Relevance 2.51

General Comments

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