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Context Info
Confidence 0.60
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 23
Total Number 26
Disease Relevance 23.27
Pain Relevance 3.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PVR) extracellular region (PVR) nucleolus (PVR)
plasma membrane (PVR) nucleus (PVR) cytoplasm (PVR)
Anatomy Link Frequency
lung 2
mitral valve 1
brain 1
musculature 1
pulmonary artery 1
PVR (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 17 99.92 Very High Very High Very High
ketamine 10 99.76 Very High Very High Very High
Inflammation 107 98.92 Very High Very High Very High
Opioid 7 97.60 Very High Very High Very High
imagery 23 97.28 Very High Very High Very High
withdrawal 22 92.96 High High
adenocard 24 89.76 High High
Inflammatory response 10 86.40 High High
agonist 18 85.92 High High
cINOD 21 85.76 High High
Disease Link Frequency Relevance Heat
Persistent Vegetative State 405 100.00 Very High Very High Very High
Targeted Disruption 1 100.00 Very High Very High Very High
Benign Prostatic Hypertrophy 156 99.88 Very High Very High Very High
Diuresis 9 99.86 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 8 99.86 Very High Very High Very High
Pulmonary Hypertension 1594 99.84 Very High Very High Very High
Cv General 4 Under Development 129 99.80 Very High Very High Very High
Respiratory Failure 11 99.80 Very High Very High Very High
Head Trauma 6 99.80 Very High Very High Very High
Overactive Bladder 554 99.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to the authors, the patient examined met all clinical requirements of PVS.
Positive_regulation (requirements) of PVS associated with persistent vegetative state
1) Confidence 0.60 Published 2007 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2245970 Disease Relevance 0.51 Pain Relevance 0.03
Here we summarize the evidence from human brain imaging as well as neurological damage in animals and humans suggesting that some form of consciousness can survive brain damage that commonly causes PVS.
Positive_regulation (causes) of PVS in brain associated with persistent vegetative state and imagery
2) Confidence 0.60 Published 2007 Journal Philos Ethics Humanit Med Section Abstract Doc Link PMC2245970 Disease Relevance 0.83 Pain Relevance 0.11
A dose-dependent increase in PVR >100 mL was apparent in men and patients aged >70 years but not in women or patients aged ?
Positive_regulation (increase) of PVR
3) Confidence 0.56 Published 2010 Journal BMC Urol Section Body Doc Link PMC2939595 Disease Relevance 0.28 Pain Relevance 0
Use of high dose of vasopressin (1.16 units/kg/h ) in another animal model of acute pulmonary hypertension led to increased PVR and decreased cardiac output with a decrease in RV contractility, leading the authors to cautioning against its use when RV function is compromised (Leather et al 2002) .
Positive_regulation (increased) of PVR associated with pulmonary hypertension and cv general 4 under development
4) Confidence 0.46 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 0.95 Pain Relevance 0
In addition to positive effects on cardiac output and systemic arterial pressure, norepinephrine increases PVR and worsens pulmonary artery hypertension (Kwak et al 2002).
Positive_regulation (increases) of PVR in pulmonary artery associated with hypertension
5) Confidence 0.46 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 0.67 Pain Relevance 0
Besides disproportional a increase in PVR phenylephrine also causes bradycardia (Tisdale et al 1995) with detrimental consequences on pulmonary and systemic hemodynamic.
Positive_regulation (increase) of PVR associated with heart rate under development
6) Confidence 0.46 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 0.86 Pain Relevance 0.07
As a pulmonary vasodilator, isoproterenol is one of the preferred inotropic agents in heart transplantation patients with elevated PVR.
Positive_regulation (elevated) of PVR in heart
7) Confidence 0.46 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 0.89 Pain Relevance 0.06
The consequence of sympathetic hyperactivity is an increase in pulmonary vascular resistance (PVR) with impedance of flow, causing RV strain that impairs filling and causes RV volume and pressure overload.
Positive_regulation (increase) of PVR in sympathetic associated with sprains and strains and attention deficit hyperactivity disorder
8) Confidence 0.46 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 1.21 Pain Relevance 0.07
An increase in PVR with ketamine has been found during spontaneous respiration.
Positive_regulation (increase) of PVR associated with ketamine
9) Confidence 0.41 Published 1995 Journal Anaesthesist Section Abstract Doc Link 8592971 Disease Relevance 0.65 Pain Relevance 0.49
Consequently, as with other antimuscarinics, it may be prudent to monitor PVR in older men starting treatment with fesoterodine, at least during the first month of treatment.
Positive_regulation (monitor) of PVR
10) Confidence 0.40 Published 2010 Journal BMC Urol Section Body Doc Link PMC2939595 Disease Relevance 0.17 Pain Relevance 0
The risk of acute urinary retention may be related to increases in PVR.
Positive_regulation (increases) of PVR associated with overactive bladder
11) Confidence 0.40 Published 2010 Journal BMC Urol Section Body Doc Link PMC2939595 Disease Relevance 0.29 Pain Relevance 0
1) Acute Traumatic and Nontraumatic Injuries: The most common acute causes of a PVS are head trauma and hypoxic-ischemic encephalopathy.
Positive_regulation (causes) of PVS in head associated with persistent vegetative state, hypoxia, head trauma, injury and brain ischemia
12) Confidence 0.40 Published 2007 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2245970 Disease Relevance 1.54 Pain Relevance 0
In support of the theory of CNS invasion due to permeation of the BBB, Yang and colleagues found that PV accumulated in the CNS of CD155 transgenic (tg) mice at a constant rate that was markedly higher than the accumulation rate for albumin, which is not believed to cross the BBB [200].
Positive_regulation (accumulation) of CD155 associated with targeted disruption and central nervous system
13) Confidence 0.38 Published 2007 Journal Virol J Section Body Doc Link PMC1947962 Disease Relevance 0.58 Pain Relevance 0.38
These simulations can be used to predict the probability of an event and to evaluate the effects of covariates, such as subject age and sex; for instance, in our work, models were used to assess the probability of increased PVR in subgroups specifically stratified by age and sex.


Positive_regulation (increased) of PVR
14) Confidence 0.38 Published 2010 Journal BMC Urol Section Body Doc Link PMC2939595 Disease Relevance 0.15 Pain Relevance 0
Airway manipulations and some induction agents can precipitate an acute increase in PVR (Hickey and Retzack 1993; Hohn et al 1999).
Positive_regulation (increase) of PVR
15) Confidence 0.33 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 0.86 Pain Relevance 0.03
In pediatric patients with pulmonary hypertension dipyridamole decreased PVR index to similar values as INO did, but with significant systemic vasodilata-tion (Ziegler et al 1998).
Positive_regulation (decreased) of PVR associated with pulmonary hypertension
16) Confidence 0.33 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605326 Disease Relevance 1.27 Pain Relevance 0.05
The electrical activity in the PVs was presumed to be a result of this extension of cardiac musculature.
Positive_regulation (result) of PVs in musculature
17) Confidence 0.28 Published 2004 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC1501062 Disease Relevance 0.51 Pain Relevance 0.03
The dynamic variables are worsening of IPSS >4 points, bothersome score > 3 points during treatment, increasing PVR, no response to alpha blockers.
Positive_regulation (increasing) of PVR
18) Confidence 0.26 Published 2007 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2721562 Disease Relevance 1.78 Pain Relevance 0.47
Persistent PH of the newborn (PPHN) occurs when PVR remains elevated after birth resulting in right to left shunting and hypoxemia.
Positive_regulation (elevated) of PVR associated with pulmonary hypertension
19) Confidence 0.24 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 1.10 Pain Relevance 0
A study by Athanasoupolos et al. demonstrated that tolterodine could safely be taken in combination with an alpha blocker in patients with urodynamically proven BOO, without the development of AUR.[19] Reynard et al. have demonstrated that anticholinergic use in BPH patients leads to a small increase in the post-void residual (PVR) without significantly increasing the risk of AUR.[20] Both these agents can be safely combined in the management of BPH, especially in patients with predominantly irritative symptoms and low PVR.
Positive_regulation (increase) of PVR associated with benign prostatic hypertrophy and overactive bladder
20) Confidence 0.17 Published 2007 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2721562 Disease Relevance 2.23 Pain Relevance 0.49

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