INT62848

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Context Info
Confidence 0.57
First Reported 1996
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 3.89
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
stomach 1
GER (Homo sapiens)
Pain Link Frequency Relevance Heat
spastic colon 7 98.24 Very High Very High Very High
anesthesia 6 96.56 Very High Very High Very High
Morphine 3 88.00 High High
palliative 2 79.08 Quite High
tolerance 1 78.20 Quite High
nud 12 22.88 Low Low
Paracetamol 12 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gastroesophageal Reflux Disease 13 100.00 Very High Very High Very High
Functional Bowel Disorder 7 98.24 Very High Very High Very High
Sleep Disorders 1 95.00 High High
Aspiration Pneumonia 1 94.32 High High
Heartburn 1 93.40 High High
Gastric Motility Disorder 50 92.96 High High
Constipation 7 92.88 High High
Diarrhoea 5 89.36 High High
Vomiting 15 86.64 High High
Dysphagia 1 84.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In an attempt to reduce GER and its complications, the authors created a surgical prosthesis coupled to an anti-reflux valve system, comparing it to the use of an esophageal prosthesis without an anti-reflux valve mechanism.
Negative_regulation (reduce) of GER associated with gastroesophageal reflux disease
1) Confidence 0.57 Published 1999 Journal Hepatogastroenterology Section Abstract Doc Link 10576361 Disease Relevance 0.80 Pain Relevance 0.15
Meperidine is not a useful addition to the anesthetic protocol if prevention of GER is desired.


Negative_regulation (prevention) of GER
2) Confidence 0.50 Published 2007 Journal Vet Anaesth Analg Section Body Doc Link 17238958 Disease Relevance 0 Pain Relevance 0
Thirty-two patients (64%) showed delayed GES, 29 (58%) delayed GEL, and 2 (4%) delayed GER.
Negative_regulation (delayed) of GER
3) Confidence 0.43 Published 1999 Journal Eur J Nucl Med Section Abstract Doc Link 10199947 Disease Relevance 0.99 Pain Relevance 0.55
GER was defined as reversible decrease in esophageal pH to less than 4.0.
Negative_regulation (decrease) of GER associated with gastroesophageal reflux disease
4) Confidence 0.42 Published 1996 Journal Anesth. Analg. Section Abstract Doc Link 8694297 Disease Relevance 0.58 Pain Relevance 0.18
A sensor-tipped catheter was used to measure esophageal pH, and GER was defined as a decrease in pH to < 4 or an increase to > 7.5.
Negative_regulation (decrease) of GER
5) Confidence 0.37 Published 2005 Journal Am. J. Vet. Res. Section Body Doc Link 15822580 Disease Relevance 0.07 Pain Relevance 0
The negative values of GER are due to larger gastric antral cross-sectional areas at 90 min, which could be due to an increase in the amount of gastric juices and saliva in the stomach.


Negative_regulation (values) of GER in stomach
6) Confidence 0.11 Published 2009 Journal Nutr J Section Body Doc Link PMC2704233 Disease Relevance 0.08 Pain Relevance 0.04
The subject that had undergone vagotomy responded in the same way as the others, showing a further reduction in the GER after drinking apple cider vinegar.
Negative_regulation (reduction) of GER
7) Confidence 0.02 Published 2007 Journal BMC Gastroenterol Section Body Doc Link PMC2245945 Disease Relevance 0.69 Pain Relevance 0
The subject that was already consuming vinegar daily before of the start of the study also showed a reduced GER after drinking apple cider vinegar.
Negative_regulation (reduced) of GER
8) Confidence 0.02 Published 2007 Journal BMC Gastroenterol Section Body Doc Link PMC2245945 Disease Relevance 0.67 Pain Relevance 0

General Comments

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