INT63223

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Context Info
Confidence 0.65
First Reported 1996
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 3.38
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Gpt) cellular_component (Gpt) biological_process (Gpt)
cytoplasm (Gpt)
Anatomy Link Frequency
PGE1 1
muscle 1
colon 1
heart 1
Gpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 4 99.92 Very High Very High Very High
Paracetamol 15 99.80 Very High Very High Very High
isoflurane 1 70.04 Quite High
Disease Link Frequency Relevance Heat
Injury 13 97.00 Very High Very High Very High
Hepatotoxicity 9 96.32 Very High Very High Very High
Body Weight 2 94.92 High High
Obesity 3 92.08 High High
Liver Disease 5 89.12 High High
Infection 3 81.36 Quite High
Hepatitis 3 80.88 Quite High
Cirrhosis 3 80.32 Quite High
Necrosis 2 76.40 Quite High
Carcinoma 1 67.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results showed that CHCKT treatments significantly decreased the level of serum glutamic oxaloacetic transaminase (sGOT) and glutamic pyruvic transaminase (sGPT) in APAP-treated groups.
Transcription (level) of glutamic pyruvic transaminase associated with paracetamol
1) Confidence 0.65 Published 2007 Journal Am. J. Chin. Med. Section Abstract Doc Link 17265552 Disease Relevance 0.43 Pain Relevance 0.44
Results showed that CHCKT treatments significantly decreased the level of serum glutamic oxaloacetic transaminase (sGOT) and glutamic pyruvic transaminase (sGPT) in APAP-treated groups.
Transcription (level) of sGPT associated with paracetamol
2) Confidence 0.65 Published 2007 Journal Am. J. Chin. Med. Section Abstract Doc Link 17265552 Disease Relevance 0.43 Pain Relevance 0.44
Quantitative real-time polymerase chain reaction (qRT-PCR) analysis shows that ALT1 messenger RNA is widely distributed and mainly expressed in intestine, liver, fat tissues, colon, muscle, and heart, in the order of high to low expression level, whereas ALT2 gene expression is more restricted, mainly in liver, muscle, brain, and white adipose tissue.
Transcription (expressed) of ALT1 in colon associated with obesity
3) Confidence 0.65 Published 2009 Journal Hepatology Section Abstract Doc Link 19085960 Disease Relevance 0.80 Pain Relevance 0
Quantitative real-time polymerase chain reaction (qRT-PCR) analysis shows that ALT1 messenger RNA is widely distributed and mainly expressed in intestine, liver, fat tissues, colon, muscle, and heart, in the order of high to low expression level, whereas ALT2 gene expression is more restricted, mainly in liver, muscle, brain, and white adipose tissue.
Transcription (expressed) of ALT1 in muscle associated with obesity
4) Confidence 0.22 Published 2009 Journal Hepatology Section Abstract Doc Link 19085960 Disease Relevance 0.80 Pain Relevance 0
Quantitative real-time polymerase chain reaction (qRT-PCR) analysis shows that ALT1 messenger RNA is widely distributed and mainly expressed in intestine, liver, fat tissues, colon, muscle, and heart, in the order of high to low expression level, whereas ALT2 gene expression is more restricted, mainly in liver, muscle, brain, and white adipose tissue.
Transcription (expressed) of ALT1 in heart associated with obesity
5) Confidence 0.22 Published 2009 Journal Hepatology Section Abstract Doc Link 19085960 Disease Relevance 0.80 Pain Relevance 0
Serum GPT levels in the PGE1 group tended to be lower than those in the control group on awakening from anesthesia and on the first postoperative day.
Transcription (levels) of Serum GPT in PGE1 associated with anesthesia
6) Confidence 0.07 Published 1996 Journal Masui Section Abstract Doc Link 8721140 Disease Relevance 0.12 Pain Relevance 0.39

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