INT64217

Context Info Confidence 0.24 First Reported 1996 Last Reported 1996 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.46

signal transducer activity (Oprm1, Oprd1) plasma membrane (Oprd1) cytoplasm (Oprd1)

Anatomy Link Frequency vagus nerve 1 Oprm1 (Rattus norvegicus) Oprd1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat opioid receptor 6 100.00 Morphine 1 100.00 vagus nerve 7 97.96 ganglionectomy 1 25.00 Neurotransmitter 1 25.00 Enkephalin 1 25.00 medulla 1 25.00

Disease Link Frequency Relevance Heat Ganglion Cysts 4 40.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

mu-Opioid receptor, the opioid receptor that shows the highest affinity for morphine, appears to induce a variety of side-effects, at least partly, directly through the mu-opioid receptor on neurons constituting the autonomic part of the vagus nerve.

mu-opioid receptor Spec (appears) Positive_regulation (induce) of opioid receptor in vagus nerve associated with opioid receptor, vagus nerve and morphine

1) Confidence 0.24 Published 1996 Journal Neuroscience Section Abstract Doc Link 8783249 Disease Relevance 0 Pain Relevance 0.46

General Comments

This test has worked.