INT65032

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Context Info
Confidence 0.47
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.63
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fgf2) extracellular space (Fgf2) extracellular region (Fgf2)
nucleus (Fgf2) embryo development (Fgf2) cytoplasm (Fgf2)
Anatomy Link Frequency
nucleus 1
astrocytes 1
Fgf2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 12 73.04 Quite High
anesthesia 2 25.00 Low Low
agonist 2 25.00 Low Low
noradrenaline 1 25.00 Low Low
Pain 1 25.00 Low Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
bDMF 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 4 99.96 Very High Very High Very High
Amputation 4 81.92 Quite High
Injury 9 75.12 Quite High
Disease 3 61.28 Quite High
Heart Rate Under Development 2 57.64 Quite High
Paralysis 11 50.72 Quite High
Pressure Volume 2 Under Development 1 50.24 Quite High
Convulsion 2 25.00 Low Low
Pain 1 25.00 Low Low
Facial Nerve Injuries 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Axotomy also elevated the number of GFAP astrocytes (143% after crush; 277% after transection) and nuclear FGF-2 (57% after transection) in astrocytes (confirmed by two-color immunoperoxidase) in the ipsilateral facial nucleus.
Positive_regulation (elevated) of in astrocytes Negative_regulation (number) of nuclear FGF-2 in nucleus
1) Confidence 0.47 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Abstract Doc Link PMC2995486 Disease Relevance 0.27 Pain Relevance 0
Local action: Plantar subcutaneous injection of bFGF at above 0.005 mg/site induced edema by itself on and after the next day, and also reinforced carrageenin-induced edema from 1 day after injection.
Positive_regulation (induced) of Negative_regulation (injection) of bFGF associated with pressure and volume under development
2) Confidence 0.33 Published 1996 Journal Arzneimittelforschung Section Abstract Doc Link 8842346 Disease Relevance 0.36 Pain Relevance 0.04

General Comments

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