INT65094

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Context Info
Confidence 0.31
First Reported 1996
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACP5) small molecule metabolic process (ACP5) lysosome (ACP5)
Anatomy Link Frequency
chondrocytes 1
ACP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 7 99.88 Very High Very High Very High
Clonidine 1 98.56 Very High Very High Very High
Snapping jaw 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 79.72 Quite High
Temporomandibular Joint Syndrome 8 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Arthropathy 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hypercalcemia 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Osteoporosis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Milium 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Catecholamines also reduced cell proliferation, increased tartrate-resistant acid phosphatase (TRAcP) activity, interleukin 6 (IL-6) production, multi-nuclearity and response to salmon calcitonin (sCT) in undifferentiated FLG 29.1 cells.
Negative_regulation (reduced) of tartrate-resistant acid phosphatase associated with catecholamine
1) Confidence 0.31 Published 1996 Journal Osteoporos Int Section Abstract Doc Link 8845594 Disease Relevance 0 Pain Relevance 0.39
-treated chondrocytes decreased TRAP staining in RAW264.7 cells.
Negative_regulation (decreased) of TRAP in chondrocytes
2) Confidence 0.18 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2829618 Disease Relevance 0.08 Pain Relevance 0

General Comments

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