INT66822

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Context Info
Confidence 0.49
First Reported 1996
Last Reported 1996
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PIGA) biosynthetic process (PIGA)
Anatomy Link Frequency
blood cells 2
PIGA (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 30.32 Quite Low
Disease Link Frequency Relevance Heat
Paroxysmal Nocturnal Hemoglobinuria 14 97.52 Very High Very High Very High
Hematological Disease 4 96.00 Very High Very High Very High
Disease 3 77.52 Quite High
Myeloid Leukemia 1 35.84 Quite Low
Leukemia 1 35.64 Quite Low
Aplastic Anemia 1 33.64 Quite Low
Abdominal Pain 1 30.32 Quite Low
Thrombosis 1 28.76 Quite Low
Hemolytic Anemia 1 25.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The occurrence of the PIG-A mutation causing the absence of GPI-linked proteins on blood cells allows the PNH clone to flourish and to maintain hematopoiesis; thus it seems that the PIG-A mutation is nature's own gene therapy and the price that these patients have to pay is PNH.
Spec (seems) Positive_regulation (occurrence) of Positive_regulation (causing) of PIG-A in blood cells associated with hematological disease and paroxysmal nocturnal hemoglobinuria
1) Confidence 0.49 Published 1996 Journal Schweiz Med Wochenschr Section Abstract Doc Link 8946596 Disease Relevance 1.00 Pain Relevance 0

General Comments

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