INT687

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Context Info
Confidence 0.42
First Reported 1978
Last Reported 1978
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Sct)
Anatomy Link Frequency
pancreas 2
Sct (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 3 99.00 Very High Very High Very High
Chronic pancreatitis 4 98.34 Very High Very High Very High
Somatostatin 2 86.84 High High
Disease Link Frequency Relevance Heat
Ulcers 2 99.04 Very High Very High Very High
Pain 2 99.00 Very High Very High Very High
Pancreatitis 4 98.34 Very High Very High Very High
Duodenal Ulcer 4 93.92 High High
Diabetes Mellitus 3 90.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In chronic pancreatitis, secretin releasing response to acidification was markedly impaired, in addition, inhibition of secretin release by bicarbonate was diminished due to a lack of bicarbonate flow from the pancreas.
Negative_regulation (diminished) of Negative_regulation (inhibition) of secretin in pancreas associated with chronic pancreatitis
1) Confidence 0.42 Published 1978 Journal Gastroenterol. Jpn. Section Abstract Doc Link 648803 Disease Relevance 0.92 Pain Relevance 0.33
In duodenal-ulcer patients, whose duodenal buffering capacity is reduced because of a relative deficiency of secretin response, this leads to pain.
Negative_regulation (reduced) of Negative_regulation (deficiency) of secretin associated with pain and ulcers
2) Confidence 0.05 Published 1978 Journal Lancet Section Abstract Doc Link 78101 Disease Relevance 0.35 Pain Relevance 0.26

General Comments

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