INT69132

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Context Info
Confidence 0.42
First Reported 1997
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.95
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACLY) mitochondrion (ACLY) small molecule metabolic process (ACLY)
nucleolus (ACLY) plasma membrane (ACLY) nucleus (ACLY)
Anatomy Link Frequency
knee 2
ligaments 1
tendon 1
external 1
ACLY (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 200 98.56 Very High Very High Very High
Pain score 1 82.60 Quite High
Pain 34 70.96 Quite High
imagery 21 65.88 Quite High
corticosteroid 2 57.80 Quite High
tolerance 2 40.76 Quite Low
Inflammation 20 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Tendonitis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 198 98.56 Very High Very High Very High
Injury 149 98.28 Very High Very High Very High
Knee Injuries 16 93.32 High High
Rupture 26 88.36 High High
Pain 32 82.32 Quite High
Tendinopathy 48 72.76 Quite High
Cicatrix 2 53.84 Quite High
Hyperplasia 4 53.68 Quite High
Knee Osteoarthritis 4 47.04 Quite Low
Body Weight 6 36.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A consecutive series of 90 athletically-active patients (67 males, 23 females) who underwent reconstruction for ACL deficiency using a patellar tendon autograft was retrospectively reviewed.
Negative_regulation (deficiency) of ACL in tendon
1) Confidence 0.42 Published 1997 Journal Arthroscopy Section Abstract Doc Link 9127072 Disease Relevance 0 Pain Relevance 0
This article reviews the knee stability assessments for injury diagnosis, treatment evaluation and long term standard for safe return-to-sports for ACL deficient knee.
Negative_regulation (deficient) of ACL in knee associated with injury
2) Confidence 0.38 Published 2009 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2744659 Disease Relevance 0.23 Pain Relevance 0
It is a reproduction of event that occurs when the knee gives way because of the loss of ACL.


Negative_regulation (loss) of ACL in knee
3) Confidence 0.38 Published 2009 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2744659 Disease Relevance 0.08 Pain Relevance 0
Unlike extraarticular ligaments, there exist several well known factors that limit the ACL from healing [178,179].
Negative_regulation (limit) of ACL in ligaments
4) Confidence 0.36 Published 2009 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2695438 Disease Relevance 0.48 Pain Relevance 0.09
By operating in both force and position control modes, the robot can apply a pre-determined external load to the specimen, such as those used for the diagnosis of ACL deficiency [222-224], and the corresponding kinematics can be obtained.
Negative_regulation (deficiency) of ACL in external
5) Confidence 0.36 Published 2009 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2695438 Disease Relevance 0 Pain Relevance 0
Unfortunately, this pathology is often unrecognized, and even if the ACL is repaired the development and progression of OA might not be prevented.


Negative_regulation (repaired) of ACL associated with osteoarthritis
6) Confidence 0.03 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526599 Disease Relevance 2.15 Pain Relevance 0.83

General Comments

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